Univerzita Palackeho V Olomouci

Jitka Ulrichova

Miroslav Strnad

Karel Dolezal

Lukas Spichal

Jiri Voller

Lucie Plihalova

Ondrej Plihal

Alena Rajnochova Svobodova

Jitka Vostalova

Marek Zatloukal

Alena Kadlecova

Hana Vylicilova

Martin Hönig

Magdalena Bryksova

Adenine derivatives substituted at the C2, N6, and N9 purine positions having antisenescent and combined photoprotective UVA/UVB effects. These substances are particularly suitable as anti-senescent and UV-photoprotective component in cosmetic preparations, plant protection preparations and in preparations for the treatment/application of tissue cultures. 

Adenine derivatives and their use as UV-photoprotective agents

6-aryl-9-glycosidpurines of general formula I and pharmaceutically acceptable salts thereof with alkali metals, ammonia, amines, or addition salts with acids, whereinGly represents &#x3b2;-D-arabinofuranosyl or &#x3b2;-D-2'-deoxyribofuranosyl,Ar represents benzyl or furfuryl, each of which can be unsubstituted or substituted by one or more, preferably one to three, substituents selected from the group comprising hydroxyl, alkyl, halogen, alkoxy, amino, mercapto, carboxyl, cyano, amido, sulfo, sulfamido, acyl, acylamino, acyloxy, alkylamino, dialkylamino, alkylmercapto, trifluoromethyl, trifluoromethoxy, for use as antisenescent and UV protective compounds in animals.

6-aryl-9-glycosylpurines and use thereof

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Olomouc, Czechia

Jitka Ulrichova