Lupin, Inc.

Jitendra Sambhaji Jadhav

Venkata Poornapragnacharyulu Palle

Rajender Kumar Kamboj

Bhavesh Dave

Samiron Phukan

Rakesh Kumar Banerjee

Abhijit Datta Khoje

Rajkumar Hangarge

Venkata P Palle

The present disclosure is related to heteroaryl compounds as MEK inhibitors. These compounds include heteroaryl compounds of formula I, their pharmaceutically acceptable salts, combinations with suitable medicament and pharmaceutical compositions thereof. The present disclosure also includes processes of preparation of the compounds and their use in methods of treatment. The compounds as disclosed herein are of Formula (I) below: 

Heterocyclyl compounds as MEK inhibitors

The present invention is related to heteroaryl compounds as MEK inhibitors. The invention includes heteroaryl compounds of formula I, their tautomers and pharmaceutically acceptable salts, combinations with suitable medicament and pharmaceutical compositions thereof. The present invention also includes process of preparation of the said compounds and intended use in therapy of them. 

Heterocyclyl compounds

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Pune, India

Jitendra Sambhaji Jadhav