Ada Foundation

Other

Jirun Sun

Rafael L Bowen

Young Lee

Nicole Ritzert

Xiaohong Wang

A multi-functional, stimuli-responsive material includes a substrate functionalized with a pH-sensitive Azo-QPS compound or co-assemblies containing Azo-QPS compounds. The Azo-QPS compound includes a positively-charged phenyl-azo-pyridinium core, an anion affiliated with the core, a head group, a tail group, a surface bonding group coupling the pH-sensitive Azo-QPS compound to the substrate, and a spacer connecting the pH-sensitive Azo-QPS compound to the surface bonding group.

Multi-functional, stimuli-responsive materials, methods of preparation, methods of use, and uses thereof

A composition of matter includes one or more functionalized vinylbenzyl components of the formula covalently connected to one or more R functional components; the one or more R functional groups selected from a group including one or more hydroxyl methyl (&#x2014;CHOH&#x2014;) moieties and/or derivatives thereof, one or more ethoxy (&#x2014;CH&#x2014;CH&#x2014;O&#x2014;) moieties and/or derivatives thereof, end one or more benzene (CH) and/or derivatives thereof; and ether links that connect the functionalized vinylbenzyl components and the R functional components.

Resin composites for use in dental preventive and restorative applications

A new azo-type quaternary pyridinium salt (Azo-QPS) shows enhanced activity at acidic conditions (e.g., pH=5); in neutral or basic conditions, this new Azo-QPS shows a much lower level (2-50 times less) anti-bacterial activity. The use of such a 'stimulus-enhance' antibiotic can response to the proliferation of bacteria directly. It helps reduce or prevent the build-up of potent antibacterial agents in the oral environment. The antibacterial properties of Azo-QPS are 'activated' when the environmental pH becomes acidic; this acidic pH may be indicative of the accumulation ofor the initiation of tooth decay.

AZO-quaternary pyridinium salts with acid-enhanced antibacterial efficacy, methods of use, methods of synthesis, and uses thereof

A composition of matter includes a mixture of styrene derivative monomers and methacrylate and/or acrylate derivative monomers, which have one or more urethane, carbamate, amide, and/or amine functional groups, and initiators, and the compositions are used to achieve composition control of the forming polymer, with the mole fraction of acrylate/methacrylate and styrene moieties in the forming polymer determined by the chemistry and composition of the feeding monomers.

Rapid azeotropic photo-copolymerization of styrene and methacrylate derivatives and uses thereof

A composition of matter includes one or more functionalized vinylbenzyl components of the formula wherein n is an integer equal to or greater than 1 covalently connected to one or more R functional components; the one or more R functional groups selected from a group including one or more hydroxyl methyl (&#x2014;CHOH&#x2014;) moieties and/or derivatives thereof, one or more ethoxy (&#x2014;CH&#x2014;CH&#x2014;O&#x2014;) moieties and/or derivatives thereof, and one or more benzene derivatives; and ether links that connect the functionalized vinylbenzyl components and the R functional components.

Enzymatically and hydrolytically stable dental preventive and restorative systems

A computer-controlled method for forming a composition-controlled product using 3D printing includes disposing two or more liquid reactant compositions in respective two or more reservoirs; and mixing the two or more liquid reactant compositions, which in turn includes controlling by the computer a mass ratio of the mixed two or more liquid reactant compositions. The computer-controlled method further includes scanning, under control of the computer, a mixed liquid reactants nozzle over a substrate; depositing the mixed liquid reactant compositions onto the substrate; and operating, under control of the computer, a light source to polymerize the deposited mixed liquid reactant compositions.

3D printing of composition-controlled copolymers

A composition of matter includes a mixture of styrene derivative monomers and methacrylate/acrylate derivative monomers, which have one or more urethane, carbamate, amide, and/or amine functional groups, and initiators, and the compositions are used to achieve composition control of the forming polymer, with the mole fraction of acrylate/methacrylate and styrene moieties in the forming polymer determined preferably by the chemistry and composition of the feeding monomers rather than the viscosity of the monomers.

A multi-functional self-healing dental composite may intrinsically repair the micro-crack and prevent the crack from propagating to catastrophic failure, thus significantly extending the service life of the restorative material. The self-healing dental composite includes a dental resin matrix, fillers, healing powder, and healing liquid containing micro-capsules distributed throughout the matrix. Each of the micro-capsules have a silica she formed by the hydrolysis condensation of TEOS in the presence of an aqueous solution of a healing liquid. The healing liquid includes a homo-polymers(s) and/or copolymer(s) of carboxylic acid(s). The healing powder particles distributed throughout the resin matrix, and include alumina, silica and other elements. The self-healing may be triggered automatically as a result of micro-cracking, induced by thereto/mechanical fatigue. During the self-healing process, antibacterial agents may be released to provide protection of the composites against cariogenic bacteria. The self-healing dental composites also may improve tooth remineralization, and caries prevention though fluoride release.

Multi-functional self-healing dental composites, methods of synthesis and methods of use

A composition of matter includes one or more functionalized vinylbenzyl components of the formula covalently connected to one or more R functional components; the one or more R functional groups selected from a group including one or more hydroxyl methyl (&#x2014;CHOH&#x2014;) moieties and/or derivatives thereof, one or more ethoxy (&#x2014;CH&#x2014;CH&#x2014;O&#x2014;) moieties and/or derivatives thereof, and one or more benzene (CH) and/or derivatives thereof; and ether links that connect the functionalized vinylbenzyl components and the R functional components.

Growing community of inventors

Rockville, MD, United States of America

Jirun Sun