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Jirun Peng

Yansheng Du

Junyi Liu

Zhizhong Ma

Disclosed is the use of the compounds represented by formula (I) in the preparation of a medicament against tumor angiogenesis, wherein Rand Rare each independently C-Calkylidene group or C-Calkenylidene group; Aand Aare each independently aryl, isoaryl, or aryl or isoaryl optionally substituted by halogen, &#x2014;CN, &#x2014;NO, &#x2014;OH, &#x2014;SH, &#x2014;OR, &#x2014;SR, &#x2014;R, &#x2014;R&#x2014;OR, &#x2014;C(O)R, &#x2014;S(O)R, &#x2014;S(O)R, &#x2014;NRR, &#x2014;C(O)OR, &#x2014;C(O)NRR, &#x2014;O(O)CR, &#x2014;S(O)CRor &#x2014;NR(O)CR, wherein Ris C-Calkyl, Rand Rare each independently hydrogen, C-Calkyl, aryl or substituted aryl; and X and Y are each independently oxygen; and the compound of formula (I) does not include phenethyl caffeate. 

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Beijing, China

Jirun Peng