Novabone Products, LLC

Usbiomaterials Corporation

Other

Changzhou Bio-sheng Technology Co., Ltd

Jipin Zhong

Jiang Chang

David C Greenspan

Gregory J Pomrink

Roy Layne Howell

Zehra Tosun

Cecilia Cao

Weiming J Gu

Yuhong Xu

Yongxiang Wang

Qiang Jie

David M Gaisser

Weiming Gu

A method of manufacturing a resorbable, macroporous bioactive glass scaffold comprising approximately 15-45% CaO, 30-70% SiO, 0-25% NaO, 0-17% PO, 0-10% MgO and 0-5% CaFby mass percent, produced by mixing with pore forming agents and specified heat treatments.

Resorbable macroporous bioactive glass scaffold and method of manufacture

A sol-gel bioactive glass precursor, method for making sol-gel glasses, resultant sol-gel bioactive glasses, and methods of use thereof, which include introducing NaO into the glass network during the sol-gel process through the use of Na-ethoxide, NaCl, or sodium silicate rather than sodium nitrate. Medical and industrial uses of such glasses.

Sodium containing sol-gel derived bioactive glasses and uses thereof including hemostasis

A method of manufacturing a resorbable, macroporous bioactive glass scaffold comprising approximately 24-45% CaO, 34-50% SiO, 0-25% NaO, 5-17% PO, 0-5% MgO and 0-1% CaFby mass percent, produced by mixing with pore forming agents and specified heat treatments.

The present invention relates to a pH buffered bioactive glass, and its preparation process and use. The pH buffered bioactive glass comprises SiO, CaO, NaO, and PO, and further comprises solid acidic particles or a Tris buffer solution. The pH buffered bioactive glass can regulate the pH of formulations comprising bioactive glass, and has a good therapeutic effect with a low dosage.

pH buffered bioactive glass, and its preparation process and use

A sol-gel bioactive glass precursor, method for making sol-gel glasses, resultant sol-gel bioactive glasses, and methods of use thereof which include introducing NaO into the glass network during the sol-gel process through the use of Na-ethoxide, NaCl, or sodium silicate rather than sodium nitrate. Medical and industrial uses of such glasses.

A settable osteostimulative bone graft putty composition having a bioactive glass particulate component composed of a long-term and a short-term component; the long-term component having particle sizes greater than 90 micrometers and the short-term component having particle sizes less than 90 micrometers; the long-term component comprising about 60% to 90% of the bioactive glass osteostimulative particulate component dry weight and the short-term component comprising about 40% to 10%; a binder component having a calcium sulfate component and a calcium silicate component; the calcium sulfate component comprising about 35% to 50% of the binder component dry weight and the calcium silicate component comprising about 65% to 50%; the bioactive glass osteostimulative particulate component being about 20% to 60% of the total putty dry weight composition and the binder being about 80% to 40%; the bioactive glass particulate component and the binder component mixable in water to form the putty.

Osteostimulative settable bone graft putty

A resorbable, macroporous bioactive glass scaffold comprising approximately 24-45% CaO, 34-50% SiO, 0-25% NaO, 5-17% PO, 0-5% MgO and 0-1% CaFby mass percent, produced by mixing with pore forming agents and specified heat treatments.

A process for making bioactive glasses is described including preparing a reaction mixture of reactants capable of forming a sol-gel, aging the reaction mixture, near equilibrium drying a gel resulting from the reaction mixture, and heating the -near equilibrium-dried gel described. Also described are near equilibrium-dried bioactive glass compositions.

Bioactive sol-gel compositions and methods

A process for making bioactive glasses is described including preparing a reaction mixture of reactants capable of forming a sol-gel, aging the reaction mixture, near equilibrium drying a gel resulting from the reaction mixture, and heating the near equilibrium-dried gel described. Also described are near equilibrium-dried bioactive glass compositions.

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Gainesville, FL, United States of America

Jipin Zhong