Dexcom, Inc.

Jiong Zou

Ted Tang Lee

Shanger Wang

Sebastian Bohm

Peter C Simpson

Sean T Saint

Paul V Neale

Ryan Everett Schoonmaker

Jason M Halac

John Michael Gray

Jennifer Blackwell

Jason Mitchell

Todd Andrew Newhouse

Michael Levozier Moore

Leah Morta Edra

John Patrick Majewski

Pradnya Prakash Samant

Robert James Boock

Mark Allan Tapsak

Stephen J Vanslyke

Anna Leigh Davis

Sebastian Böhm

Disha B Sheth

Maria Noel Brown Wells

Huashi Zhang

Rui Ma

Jonathan Hughes

Neel Narayan Shah

Minglian Shi

Andrew Trinin Dennis

Jeff T Suri

Liang Wang

Wenjie Lan

David Sze

Devon M Headen

Maria Neol Brown Wells

Disclosed are devices for determining an analyte concentration. The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and an electronics unit operatively connected to the sensor. The electronics unit may be engaged with a housing that may secure the device to a host's skin. In this regard, in one embodiment, the housing may be attached to an adhesive patch that is fastened to the skin of the host.

Analyte sensor

Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The enzyme layer protects the enzyme and prevents it from leaching from the sensing membrane into a host or deactivating.

Enzyme immobilized adhesive layer for analyte sensors

Sensor devices including dissolvable tissue-piercing tips are provided. Methods of using and fabricating sensor devices are also provided.

Sensors for continuous analyte monitoring

Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

Transcutaneous analyte sensor systems and methods

Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises a biointerface layer which interfaces with a biological fluid containing the analyte to be measured. The biointerface layer can comprises a biointerface polymer, wherein the biointerface polymer comprises polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The sensing membrane can also comprise an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The sensing membrane can also comprise a diffusion-resistance layer, which can comprise a base polymer having a lowest Tg of greater than &#x2212;50 C.

Membrane layers for analyte sensors

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San Diego, CA, United States of America

Jiong Zou