Nuctech Company Limited

Tsinghua University

Apple Inc.

Huawei Technologies Co., Limited

Ningbo Innovative Mechanism Bioscience LLC

Other

Beijing Unisoc Communications Technology Co., Ltd.

Nutech Company Limited

Beijing Textile Research Institute

Beijing Youcare Kechuang Pharmaceutical Technology Co., Ltd.

Jinyu Zhang

Li Ni Zhang

Zhiqiang Chen

Yuanjing Li

Yinong Liu

Hu Tang

Ziran Zhao

Hua Peng

Haifeng Hu

Xuewu Wang

Yumin Yi

Huaning Niu

Yaohong Liu

Qingjun Zhang

Shangmin Sun

Jeongho Jeon

Wenting Chang

Yuxiang Xing

Yanli Deng

Salvatore Talarico

Guang Yang

Ming Ruan

Junli Li

Yuan Zhu

Qingping Huang

Quanwei Song

Lan Zhang

Yushu Zhang

Dae Won Lee

Yang Tang

Alexei Vladimirovich Davydov

Candy Yiu

Kyeongin Jeong

Ming Jin Chen

Qiaoyang Ye

Honglei Miao

Jianmin Li

Meng Wang

Wanlong Wu

Chuanxiang Tang

Yulan Li

Li Zhang

Hongxin Wu

Wei Jia

Hui Ding

Yali Xie

Siyuan Liang

Zhanjun Duan

Bin Sang

Huaping Tang

Qingqing Zhou

Haitao Jiang

Huaqiang Wu

Jin Ping Lin

Guoliang Li

Yangtian Zhang

He Qian

Fei Fang

Honglei Zhang

Zhongxia Zhang

Zhanfeng Qin

Hailin Wang

Zhizhong Liang

Zhongrong Yang

Kai Dong

Lian Wang

Yongming Wang

Liwei Song

Mei Zhang

Xin Qu

Sihao Li

Shifu Li

Pinggao Zhou

Huanyu Wang

Longsong Ran

Qianlu Ren

Xiaoti Yin

Ming Chen

Hongming Lyu

Zhiping Yu

Yilin Huang

Yumin Zhu

Lei Liao

Zirao Zhao

Xiang'an Qi

Haihong Sun

Xia Song

Ximeng Li

Yahui Dong

Gengshen Song

Xiaowen Yu

Lijie Jin

Yuting Zhou

Zhongliang Zhang

Qinchan Wang

The present disclosure relates to the technical field of molecular biology and provides a lipid composition targeting antigen-presenting cells and a use thereof. The composition provided by the present disclosure demonstrates good organ and cell targeting specificity, significantly enhancing the protein expression level of antigens in the spleen. Additionally, the composition significantly increases the percentage of cells that express the antigen among antigen-presenting cells (e.g., B cells, pDC cells, cDC cells, and macrophages) in the spleen, indicating that the composition can be used in the immunotherapy of diseases.

Lipid composition targeting antigen-presenting cells and use thereof

Fusion Protein And Composition For Treating Animal Tumors

A protein molecule that includes interleukin 12a (IL12a), interleukin 12b (IL12b), a first factor and a second factor located in the same polypeptide chain that can be used for treating tumors.

Protein molecule of interleukins 12a and b combined with additional factors

Embodiments of the present disclosure provides a feedback method and apparatus, SCI sent by a second UE to a first UE is used to indicate N time-frequency resources, the second UE sends a PSSCH to the first UE on each of the N time-frequency resources, the N PSSCHs correspond to the same TB, the first UE determines L time-frequency resources according to the N time-frequency resources indicated by the first SCI, and time domains of PSFCH resources respectively corresponding to the L time-frequency resources are the same. Afterwards, the first UE feeds back to the second UE according to the PSFCH resource and received PSSCH.

Feedback method and apparatus

Some embodiments provide a microservice component-based database system, to split a database kernel into microservice components that can be enabled and run independently and whose functions are decoupled, and implement flexible database assembly and management. The microservice component can be deployed based on a system resource and a service form. The components can collaborate with each other by using a lightweight communication mechanism. A component manager provides capabilities such as registration and deregistration of a service component, component resource management, component fault tolerance, and component upgrade, to implement dynamic management of the component in a running environment. A job scheduler selects, based on a job submitted by a user, an optimal execution path including a plurality of components, and performs resource management and scheduling in a job execution process, to implement load balancing and high availability.

Microservice component-based database system and related method

Disclosed are a protein heterodimer and the use thereof. The protein heterodimer comprises a first polypeptide chain and a second polypeptide chain different from the first polypeptide chain, wherein the first polypeptide chain comprises IL(interleukin)12a and a first factor fused to IL12a, the second polypeptide chain comprises IL12b and a second factor fused to IL12b, and the first factor and the second factor are each independently selected from a group consisting of: IL2, GMCSF(granulocyte-macrophage colony-stimulating factor), IL7, IL15, IL21 and FLT3L(FMS-like tyrosine kinase 3 ligand). The protein heterodimer can be used for treating tumors.

Protein heterodimer and use thereof

A user equipment (UE) may assess a radio link quality of a plurality of frames for communication, via the interface to the RF circuitry, with a radio access network (RAN) node. When the radio link quality of a frame, of the plurality of frames, is below an out-of-sync (OOS) threshold, the UE may indicate that the frame is OOS. When the radio link quality of a frame, of the plurality of frames, is above an in-sync (IS) threshold that the frame is IS. Additionally, or alternatively, the UE may process information, received from the RAN node indicating a partial subframe, of a subframe, to be used to transmit uplink control information (UCI) to the RAN node. The UE ma also perform UCI mapping for using of the partial subframe to transmit UCI via a physical uplink control channel (PUSCH), and proceed by using the partial subframe to communicate the UCI to the RAN node.

Managing link quality and using partial subframes in wireless telecommunication networks

Provided is a cytokine combination for treating a tumor and/or preventing recurrence or metastasis of the tumor. The cytokine combination comprising at least three cytokines selected from the following groups: IL(interleukin)12 or a functional variant thereof, GMCSF (granulocyte-macrophage colony-stimulating factor) or a functional variant thereof, FLT3L (FMS-like tyrosine kinase 3 ligand) or a functional variant thereof, IL2 or a functional variant thereof, IL15 or a functional variant thereof, IL21 or a functional variant thereof, and IL7 or a functional variant thereof. Also provided is a nucleic acid molecule encoding the cytokine combination and a vector thereof, a cell, a pharmaceutical composition, and a application thereof for the manufacture of a drug for treating the tumor and/or preventing recurrence or metastasis of the tumor.

Cytokine combination

Described is an apparatus of a User Equipment (UE). The apparatus may comprise a first circuitry and a second circuitry. The first circuitry may be operable to process a first Downlink Control Information (DCI) format 0A transmission indicating a Grant-less Uplink (GUL) activation. The first circuitry may also be operable to process a second DCI format 0A transmission indicating a GUL release. The second circuitry may be operable to generate one or more Uplink (UL) transmissions for an unlicensed spectrum of the wireless network after the GUL activation and before the GUL release.

Downlink control information (DCI) format for grant-less uplink transmission (GUL)

Described is an apparatus of an Evolved Node-B (eNB) operable to communicate with a User Equipment (UE) on a wireless network. The apparatus may comprise a first circuitry, a second circuitry, and a third circuitry. The first circuitry may be operable to process one or more configuration transmissions from the eNB carrying one or more parameters for Grantless Uplink (GUL) transmission. The second circuitry may be operable to determine one or more GUL subframes of an acquired Maximum Channel Occupancy Time (MCOT) on time-domain resources allocated for GUL transmission from the UE. The third circuitry may be operable to generate a GUL transmission during the one or more GUL subframes of the acquired MCOT in accordance with the one or more parameters for GUL transmission.

Maximum channel occupancy time sharing and co-existence

Described is an apparatus of an Evolved Node-B (eNB) operable to communicate with a User Equipment (UE) on a wireless network. The apparatus may comprise a first circuitry and a second circuitry. The first circuitry may be operable to determine a first Timing Advance (TA) for Scheduled Uplink (SUL) transmission. The circuitry may also be operable to determine a second TA for Grantless Uplink (GUL) transmission. The second circuitry may be operable to generate an SUL transmission for transmission at a timing based upon the first TA. The second circuitry may also be operable to generate a GUL transmission for transmission at a timing based upon the second TA.

Timing advance for grantless uplink transmission

Technology for a user equipment (UE) operable to decode grant less downlink control information (G-D 5 CI) received from a Next Generation NodeB (gNB) is disclosed. The UE can decode the G-DCI received from the gNB in a MulteFire system. The UE can identify grant less uplink DCI components included in the G-DCI. The UE can perform a grant less uplink transmission with the gNB based on the grant less uplink DCI components in the G-DCI received from the gNB.

Configuration of grant-less uplink transmissions for a user equipment

This disclosure provides a clustering storage method and apparatus. The method includes: storing to-be-stored first data row by row into a local memory in a database system; determining a first sorting column, where the first sorting column is used to sort data that has been cached in the local memory; sorting second data according to the first sorting column if the second data that has been cached in the local memory meets a preset condition, where the second data is data, which has been cached into the local memory, in the first data; and storing the sorted second data in a clustering manner into a storage medium in the database system.

Clustering storage method and apparatus

A communication device including a first directional antenna and a second directional antenna which may each be set to any one of a plurality of main beam directions for radio communication, a transceiver configured to determine a reception quality for at least some of the plurality of main beam directions using the first directional antenna and for at least some of the plurality of main beam directions using the second directional antenna, select a main beam direction of the plurality of main beam directions based on the reception qualities determined by the first directional antenna and based on the reception qualities determined by the second directional antenna, and perform communication using the selected main beam direction.

Communication device and method for selecting a beam direction

Machine-readable media, methods, apparatus and system for beam acquisition in a wireless system are disclosed. In some aspects, a base station may include a transceiver configured to map beam reference signals onto a plurality of transmission beams. The base station may further include a control module configured to divide the transmission beams into a plurality of groups, based at least in part on a plurality of logical indexes assigned to the transmission beams. The control module may be further be configured to divide the transmission beams of each of the groups into a plurality of sub-groups. The control module may be further configured to change a transmission beam order in at least one of the groups, in order to equalize and maximize logical index differences between transmission beams, which are adjacent to one another in a respective sub-group.

Method, apparatus and system for beam acquisition in a wireless system

Growing community of inventors

Beijing, China

Jinyu Zhang