Ribomic Inc.

Cellmid Limited

Jinyan Wang

Takashi Matsui

Masatoshi Fujiwara

Sadatoshi Sakuma

Yoshikazu Nakamura

Akio Suzumura

Shin Miyakawa

The inventors examined the role of MK in experimental autoimmune encephalomyelitis, which is a human model for multiple sclerosis. As a result, they discovered that MK has the effect of inhibiting regulatory T cells, and that the autoimmune mechanism induced by type 1 helper T cells can be suppressed by inhibiting MK expression or its activity, thereby increasing the number of regulatory T cells. Furthermore, it was found that diseases associated with the functional disorder of regulatory T cells can be treated with the administration of an inhibitor that inhibits MK expression or activity.

Methods for treatment or prevention of diseases associated with functional disorder of regulatory T cells

Method for treatment or prevention of disease associated with functional disorder of regulatory T cell

Growing community of inventors

Aichi, Japan

Jinyan Wang