Tyco Electronics (shanghai) Co., Ltd.

Weishang (shanghai) Bio-pharmaceutical Co., Ltd.

Jinqiang Zhang

Zhigang Song

Haibo Zhang

Zhiyun Zhong

Jiahui Chen

Wei Zhong

Jiangbo Qin

A quinazoline derivative (represented by the formula (I)) salt's crystal form, a preparation method and application are provided; specifically, the hydrochloride crystal form A, B, C, D, F, H, I, Sulphate crystal form A, Maleate crystal form A, Succinate crystal form A, Adipate crystal form A, Glycolate crystal form A, Malate crystal form A, Fumarate Salt crystal form A, besylate crystal form A, B, C, benzoate crystal form A, hippurate crystal form A and oxalate crystal form A of the quinazoline derivative represented by formula (I). The salt crystal form provided by the present invention has good stability, which can be used in the treatment of non-small cell lung cancer brain metastasis, meningeal metastasis, primary brain cancer or glioma, etc., and has good bioavailability, which is of great significance for further research on the efficacy of such solid drugs.

Quinazoline derivative salt crystal form, preparation method and application

A fiber optic connector comprises an outer housing, an inner housing installed in the outer housing, a fiber optic ferrule accommodated in the inner housing, an optical cable inserted into the inner housing and connected to the fiber optic ferrule, an elastic boot that is wrapped around both a connecting portion of the fiber optic ferrule connecting to the optical cable and a portion of the optical cable adjacent to the connecting portion, and a sealing structure. The sealing structure is disposed between a rear end portion of the outer housing and the elastic boot to provide a seal between the outer housing and the elastic boot.

Fiber optic connector

A connector that includes an outer housing having an assembly channel with a stopping step on an inner wall of thereof and an optical beam expanding module assembled with the assembly channel of the outer housing. The optical beam expanding module includes a rear seat, formed with a snap ring groove, in which a C-shaped snap ring is fitted. A cable having a strengthening element is fixed on a rear end portion of the rear seat. When the cable of the optical beam expanding module is pulled outwardly, the C-shaped snap ring abuts against the stopping step, so that a pulling force exerted on the cable is transferred to the outer housing through the strengthening element of the cable, instead of being transferred to an optical fiber of the cable, thus preventing the optoelectronic coupling end faces of the connector from being separated.

Connector

Growing community of inventors

Shanghai, China

Jinqiang Zhang