Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd.

Medshine Discovery Inc.

Xiamen Moext Intelligent Technology Co., Ltd.

Jinming Huang

Fei Hong

Juan Yu

Shuhui Chen

Jian Li

Zhifei Fu

Miaorong Luo

Zhiliang Chen

Tingting Yin

Jinxia Lin

Zhiyi Luo

Jinxiang Zeng

Limei Yang

Xuxin Li

Haiying He

Wentao Wu

Zhigan Jiang

Zhixiang Li

Jian Qin

Xiaoping Zheng

Yichao Zhuang

Shicong Wang

Longhui Gao

Zhaoqiang Zhang

Binhua Gong

Disclosed is a method for preparing a pyrrolidinyl urea derivative, which acts as a TrkA inhibitor, and further disclosed are an intermediate compound of a compound of formula (I) and a preparation method therefor.

Method for preparing pyrrolidinyl urea derivative

A crystal form of a pyrazin-2(1H)-one compound and a preparation method therefor. The present invention specifically related to a compound of formula (II) and a preparation method for a crystal form of the compound. 

Crystal forms C and E of pyrazin-2(1H)-one compound and preparation method therefor

Disclosed are a crystal form (I) as an inhibitor of ACC1 and ACC2, a preparation method therefor, and the use thereof in the preparation of a drug as an inhibitor of ACC1 and ACC2. 

Crystal form as inhibitor of ACC1 and ACC2, and preparation method therefor and use thereof

Provided are preparation methods for the chemical compound represented by formula (I) and an intermediate thereof. 

Pyrazine-2(1H)-ketone compound preparation method

A total flavonoid extract fromKitam., comprising 80-85% of rutin. A preparation method comprises selecting a complex enzyme consisting of a specific composition and ratio of enzymes for enzymatic hydrolysis, extracting and concentrating by a macroporous resin, and separating and purifying by a macroporous resin. The extract has therapeutic effect on non-alcoholic fatty liver disease.

Total flavonoid extract fromKitam., preparation method thereof, and use of same in treating non-alcoholic fatty liver disease

A total flavonoid extract fromKitam., comprising, in weight percent, 80-85% of rutin. A method for preparing the total flavonoid extract fromKitam. comprises solvent extraction, complex enzymatic hydrolysis, and separation and purification by a macroporous resin. The total flavonoid extract fromKitam. is used to prepare a drug or health product related to alcoholic fatty liver disease.

Total flavonoid extract from Gynura formosana Kitam., preparation method thereof, and use of same in preparing drug or health product related to alcoholic fatty liver disease

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Jinming Huang