Shanghai East Hospital

Shanghai Changyuan Wayon Circuit Protection Co., Ltd.

Jinhua Yang

Jun Wang

Takuya Matsumoto

Yi Liu

Yutang Liu

Daohua Gao

Zhengping Liu

Zhen Cheng

Subas Man Sakya

Yihan Chen

Dandan Liang

Quantao Li

Duanyang Xie

Dan Shi

Tianju Sun

Ke Xiong

Provided are ion channel antagonists/blockers and uses thereof. Specifically, it provides the compounds of formula (I) or pharmaceutically acceptable salts, stereoisomers, solvates or prodrugs, preparation method therefor and application thereof. Definition of each group in the formula can be found in the specification for details. Provided is also pharmaceutical composition useful for treatment of heart disease and other ion channel related diseases.

Ion channel antagonists/blockers and uses thereof

A surface-mount type over-current protection element includes two single-layer composite chips, wherein one chip is made of a first core material and a first and a second metallic foil layer attached on the two surfaces of the first core material, the other chip is made of a second core material and a third and a fourth metallic foil layer attached to the two surfaces of the second core material. The protection element also has an insulating layer arranged between the two chips to electrically insulate and bond to the second and third metallic layers to form a bi-layer composite chip. Part of the first metallic foil layer and the corresponding part of the fourth metallic foil layer are etched to expose part of the first core material and correspond part of the second core material. One or more through-holes are made on the bi-layer composite chip for mounting.

Surface-mount type overcurrent protection element

Growing community of inventors

Shanghai, China

Jinhua Yang