Millennium Pharmaceuticals Limited

Cor Therapeutics, Inc.

Jingmei Zuckett

Robert M Scarborough

Penglie Zhang

Bing-Yan Zhu

Yonghong Song

Erick A Goldman

Lingyan Wang

Wenrong Huang

Wenhao Li

Novel benzamide compounds including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating coagulation disorders.

Benzamides and related inhibitors of factor Xa

Benzamides and related inhibitors of factor XA

Novel benzamide compounds including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compound and compositions are useful in vitro or in vivo for preventing or treating coagulation disorders.

Novel benzamide compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.

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Bellevue, WA, United States of America

Jingmei Zuckett