Chinese Academy of Sciences

State Grid Corporation of China

China Electric Power Research Institute Company Limited

State Grid Sichuan Electric Power Company

Jinghua Yan

Yan Li

Bo Li

Yi Shi

Qiang Ding

Zhen Sun

Guodong Huang

Mei Liu

Dan Xu

Jiali Zhang

Kun Xu

Peijun Li

Sai Dai

Hui Cui

Lianpan Dai

Tianyi Zheng

Zhi Cai

Yaling An

Fu Gao

Chenxu Hu

Chuancheng Zhang

Zelei Zhu

Deyue Men

The embodiments of the present disclosure relate to antigens of &#x3b2;-coronaviruses, preparation methods and uses thereof. The amino acid sequence of the antigen of the &#x3b2;-coronavirus includes an amino acid sequence arranged in a (A-B)-(A-B) pattern or an amino acid sequence arranged in a (A-B)-C-(A-B) pattern or an amino acid sequence arranged in a (A-B)-(A-B') pattern or an amino acid sequence arranged in a (A-B)-C-(A-B&#x2032;) pattern. The antigen of the &#x3b2;-coronavirus has a single-chain dimer structure. A single-chain dirtier expressed according to examples of the present disclosure is stable in content and has excellent immunogenicity as an antigen of a &#x3b2;-coronavirus, and a vaccine prepared by using the single-chain dimer as an antigen of a &#x3b2;-coronavirus can elicit high-titer neutralizing antibodies in mice.

Antigens of &#x3b2;-coronaviruses, preparation methods and uses thereof

Embodiments provide a method for constructing a future-state power grid model and device, including that: a current power grid model, an equipment power-off plan, an equipment retirement plan and an equipment addition plan are acquired; then, equipment is added according to the current power grid model, and an added equipment information set, a retired equipment information set and a powered-off equipment information set are determined according to the equipment addition plan, the equipment retirement plan and the equipment power-off plan respectively; and finally, a state of the added equipment is set to be an operating state, an initial network model of each period is formed according to a time sequence, and a future-state network model is constructed according to the added equipment information set, the retired equipment information set, the powered-off equipment information set and the initial network models. The embodiments further provide construction equipment and a storage medium.

Method for constructing a future-state power grid model, device and equipment and storage medium

Growing community of inventors

Beijing, China

Jinghua Yan