Shenyang Pharmaceutical University

Jinghai Zhang

Yanfeng Liu

Chunfu Wu

Runlin Ma

Yong Cui

Siling Wang

The present application relates to inhibitors of VGSC&#x3b2;3 protein and use thereof and methods of using the VGSC&#x3b2;3 protein or an inhibitor thereof to diagnose, prevent and treat cancer, and to screen antineoplastic agents using the VGSC&#x3b2;3 Protein or its regulatory sequences.

Target of VGSC &#x3b2;3 protein for prevention, treatment and diagnostic detection of cancers

The present invention relates to a peptide having analgesic and antitumor activity derived from the scorpion and partial fragment, derivative or analogue thereof having analgesic and antitumor activity, and preparation method and use thereof. The peptide having analgesic and antitumor activity is obtained by extraction, isolation and purification from the scorpion or scorpion venom. The peptide having analgesic and antitumor activity derived from the scorpion and partial fragment, derivative or analogue thereof can be obtained by chemical synthesis method or bioengineering method. The peptide having analgesic and antitumor activity derived from the scorpion and partial fragment, derivative or analogue thereof is used as the analgesic and antitumor drugs.

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Shenyang, China

Jinghai Zhang