Hemosmart Medical Technology Ltd.

Hohai University

China Three Gorges Corporation

Jing Yan

Bauer Wolfgang-Andreas Christian

Ziyi Yu

Yang Yang

Yang Yu

Hanqing Zhao

Hongwu Tang

Xiaoli Wang

Limo Tang

Charmet Jerome

Weiwei Ma

Jie Wang

Jerome Charmet

Jinyu Zheng

A microfluidic sample processing device, capable of automatically processing a microfluidic sample, comprises: a tray apparatus, for accommodating a reagent and a chip clamp for mounting a microfluidic chip; a mechanical arm, having a connecting head for connecting the chip clamp, a gas flow channel for communicating with an inner cavity of the chip clamp being arranged in the connecting head; a negative pressure suction apparatus, for providing negative pressure to the gas flow channel of the connecting head; a lifting apparatus, for driving the connecting head to rise and fall; and a translation apparatus, for driving the connecting head to move to above the chip clamp or above the reagent; wherein, the tray apparatus is positioned below the mechanical arm, and the mechanical arm is arranged on the translation apparatus and is connected to the lifting apparatus.

Device for treating microfluidic sample

Disclosed is an apparatus for enriching and screening a target object such as a cell, bacteria or biomolecule from a sample. The apparatus includes a plurality of multi-channel mesh bodies arranged in parallel, and each multi-channel mesh body includes a mesh body formed by intersecting a plurality of threads, a plurality of screen pores formed by intersecting the plurality of threads, and a capturing layer formed on the mesh body. The capturing layer includes a capturing material specifically binding with the target object.

Apparatus for enriching and screening target object such as cell, bacteria or biomolecule from sample

A method for determining flow velocity distribution in the roughness sublayer is provided, which uses the experimental device that includes a variable-slope circulating flume system and a flow-measuring system, the variable-slope circulating flume system is used to study flow in the roughness sublayer, and the flow-measuring system is used to measure flow velocity in each zone in the flume. In the variable-slope circulating flume, the method according to the invention uses cylindrical aluminum rods to simulate large-scale roughness elements, and the submergence, the average bulk flow velocity and the distribution density of roughness elements are changed.

Method for determining flow velocity distribution in roughness sublayers

Disclosed is a method for capturing target cells or molecules in solution, comprising steps of: (I) getting medium containing said target cells or molecules into an apparatus comprising a capturing device for capturing said target cells or molecules; (II) getting said medium flow through said capturing device; (III) removing unbound debris, cells and molecules; (IV) getting said target cells or molecules detached from the capturing device; and (V) collecting said target cells or molecules; wherein said capturing device comprises at least one functionalized mesh comprising a mesh substrate and a functional layer formed on said mesh substrate, wherein said functional layer comprises capturing substances that can specifically bind with said target cells or molecules. The method has high specificity, as well as high throughput, and is suitable for capturing cells or molecules in a solution or expressed at the surface of cell membranes. It is particularly suited to capture and sort circulating tumor cells.

Method for capturing target cells or molecules in solution

Growing community of inventors

Jiangsu, China

Jing Yan