The Coca-cola Company

Changchun Meihe Science and Technology Development Co., Ltd.

Global Bio-chem Technology Group Company Limited

Changchun Institute of Biological Products, Ministry of Public Health

Changchum Meihe Science and Technology Development Co., Ltd

Jing Liu

Hongbin Qi

Haiyu Ren

Indra Prakash

Yu Shi

Marlon Salvador Morales

Robert M Kriegel

Ronald D Moffitt

Wei Wang

Yi Yuan

Pengfu Wang

Guangpu Li

Baosheng Xie

Zongming Song

Shuyan Li

Xizhen Guangpu Zhang

Zongju Wan

Hui Lin

Yuhong Li

Jing Li

Yong Xue

Ling Zhang

Lingjiu Liu

Ben Liang

Yang Yi

Ying Yu

Jingye Liu

Zhouwen Xu

Provided is a method for preparing a diol. In the method, a saccharide and hydrogen as raw materials are contacted with a catalyst in water to prepare the diol. The employed catalyst is a composite catalyst comprised of a main catalyst and a cocatalyst, wherein the main catalyst is a water-insoluble acid-resistant alloy; and the cocatalyst is a soluble tungstate and/or soluble tungsten compound. The method uses an acid-resistant, inexpensive and stable alloy needless of a support as a main catalyst, and can guarantee a high yield of the diol in the case where the production cost is relatively low.

Methods for preparing diol

Disclosed are bio-based mono-ethylene glycol (MEG) compositions containing from about 1 ppm to about 5000 ppm of at least one C3-C12 1,2-diol, bio-based polyester compositions made therefrom, and methods of making the same are disclosed. Preforms and blow-molded polyester containers prepared from the bio-based MEG and polyester are described.

Bio-based MEG and polyester compositions and methods of making the same

Disclosed are bio-based polyester fibers, particularly a PET fibers, and a method of making the same by: contacting bio-based MEG composition with a diacid composition to form a polyester composition; and spinning and/or drawing the resulting polyester composition into a fiber; wherein the bio-based MEG composition comprises: a) monoethylene glycol (MEG); and b) from about 1 ppm to about 5000 ppm of at least one C3-Cy2 1,2-diol, wherein the C3-Cj2 1, 2-diol is linear, branched, or cyclic.

Bio-based MEG and polyester fiber compositions and methods of making the same

An acid-resistant alloy catalyst, comprising nickel, one or more rare earth element, tin, aluminum and molybdenum. The catalyst is cheap and stable, does not need a carrier, can be stably applied in industrial continuous production, and can lower the production cost.

Acid-resistant alloy catalyst

Disclosed is an acid-resistant alloy catalyst comprising nickel, one or more rare earth elements, stannum and aluminum. The acid-resistant alloy catalyst is low-cost and stable, and does not need a carrier, and can be stably used in continuous industrial production, thus achieving a low production cost.

Disclosed is an acid-resisting alloy catalyst comprising nickel, one or more rare earth elements, stannum and aluminum. The acid-resistant alloy catalyst is low-cost and stable, and does not need a carrier, and can be stably used in continuous industrial production, thus achieving a low production cost.

The present invention relates to a process for separation of diols from a mixture comprising diols and polyols, for example, from a reaction mixture obtained from hydrogenolysis of sorbitol. In particular, the present invention relates to separation of diols from the mixture using a combination of a wiped-film evaporator and a molecular evaporator to obtain diols in a high yield.

Separation of diols from a mixture comprising diols and polyols

The present invention relates to hepatitis A vaccine, especially to a lyophilized attenuated hepatitis A vaccine which can be stored at ambient temperature for extended periods of time, and to a method for producing the same. The present invention further relates to a stabilizer for lyophilized live vaccine and its use in improving thermostability of lyophilized live vaccine during lyophilization processing and storage period after lyophilization.

Freeze-dried hepatitis A attenuated live vaccine and its stabilizer

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Changchun, China

Jing Liu