Princeton University

Memorial Sloan Kettering Cancer Center

Jing Fan

Joshua D Rabinowitz

Craig B Thompson

Gregory S Ducker

Jurre Kamphorst

Jiangbin Ye

A 10-formyl-THF pathway for producing NADPH is useful in the diagnosis and treatment of cancer and metabolic disease, in the development of new antineoplastic agents and/or regimens, in the development of new methods for measuring metabolic pathway activity, and in the development of new therapeutics for treating metabolic disease.

NADPH production by the 10-formyl-THF pathway, and its use in the diagnosis and treatment of disease

Methods and compositions for treating cancer and other disorders associated with undesired cellular proliferation are provided comprising administering to a subject in need thereof an amino acid mixture, wherein the amino acid mixture comprises glycine, optionally comprising at least a 2:1 molar ratio of glycine to serine.

Dietary supplements and composition for treating cancer

Growing community of inventors

Madison, WI, United States of America

Jing Fan