Marine Biomedical Research Institute of Qingdao Co., Ltd.

Qingdao Conson Pharmaceutical Co., Ltd.

Qingdao Haiji Biomedicine Co., Ltd.

Jinbo Yang

Jun Zhao

Chenyang Zhao

Qiaoling Song

Lijuan Wu

Huashi Guan

Yu Tang

Dan Yao

Ximing Xu

Menglin Yang

Youjing Lv

Guangli Yu

The present disclosure discloses the use of Tegaserod or a pharmaceutically acceptable salt thereof as a JAK-STAT3 signaling pathway inhibitor and an immunomodulator in the preparation of an anti-tumor drug. Tegaserod and the pharmaceutically acceptable salt thereof show a very excellent inhibitory effect on the growth of various tumor cells in vivo and in vitro, and are expected to be used in the treatment of various cancers.

Use of tegaserod in preparation of anti-tumor drug

An application of a glucan in the preparation of a drug. A β-1,3/1,6-glucan is used for preparing a pharmaceutical composition or formulation. The pharmaceutical composition or formulation can enhance the antitumor effect of immunotherapy, radiotherapy, or chemotherapy, and is used for treating leukopenia and/or thrombocytopenia.

Application of glucan in preparation of drug

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Shandong, China

Jinbo Yang