Nanjing University of Chinese Medicine

Jinao Duan

Sheng Guo

Ming Zhao

Pei Liu

Mengtong Jiang

Shuo Cai

Rui Liu

Kexuan Zhao

Shulan Su

Hui Yan

Weimeng Feng

Junfei Zhou

Lu Fan

Di Di

Cai Lu

Mingming Xu

The invention discloses a (9β-H)-pimarane skeleton diterpenoids with anti-colon cancer activity and a derivative thereof, and further discloses a preparation method and application of the compounds above; the invention finds that novel skeleton compounds 1 and 2 have certain inhibition effects on colon cancer cells, wherein the compound 2 has remarkable anti-proliferation effects on two colon cancer cell lines HT-29 and SW620, and the effects are both stronger than those of a positive drug 5-fluorouracil, so that the compound has the potential of being developed into a new anti-colon cancer drug.

(9beta-H)-pimarane mother nucleus diterpenoid compound with anti-colon cancer activity and derivative thereof, and preparation method thereof

A strain separation method for preventing and controlling early bolting of, and preparation of a microbial agent and use thereof, the strain is obtained by separation, purification and cultivation from rhizosphere soil of, and is identified asspp. by Microbial 16S rDNA sequencing; the strain was deposited at China Center for Type Culture Collection on Jun. 24, 2021 under CCTCC NO: M 2021767; tTheXG3 strain provided by the present invention can promote the seed germination ofand delay the flowering offor about 2 days; according to field test verification, the microbial agent can increase the root weight, root diameter and rootlet number of, can effectively prevent and control early bolting of

strain for preventing and controlling early bolting of, microbial agent and use thereof

Disclosed are a deer-derived specific peptide and a detection method therefor; by screening through a large number of experiments, a ratio of relative contents of two deer-derived peptides is determined, and a graph is drawn by using a proportion of a deer antler gelatin in a mixed gelatin as an abscissa and using a value of A/Aas an ordinate; the proportion of the deer antler gelatin is linear with A/Aas a standard curve equation to distinguish a deer hide gelatin from the deer antler gelatin; the method can be used for distinguishing the deer antler gelatin from the deer hide gelatin, and controlling the quality; a defect in the prior art that the deer antler gelatin and the deer hide gelatin are difficult to distinguish in appearance, and are also difficult to distinguish by using a specific peptide fragment, is solved.

Deer-derived specific peptide and detection method therefor

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Nanjing, China

Jinao Duan