Sk Biopharmaceuticals Co., Ltd.

Jin Yong Chung

Ji Won Lee

Hye Kyung Min

Ji Yeon Kim

Ju Young Lee

Chan Mi Joung

Eun Ju Choi

Young Koo Jang

Cheol Young Maeng

Nahm Ryune Cho

Yong Je Shin

Chun Eung Park

Jong Sil Park

Yeo Jin Yoon

Joon Heo

Han Ju Yi

Young Soon Kang

Eun Ju Ryu

Seung Mo Ham

Yong Gil Kim

Joo Young Park

Ki Ho Lee

Eun Hee Chae

Hyo Jun Jung

Seung Nam Han

Soo Bong Cha

In Suk Park

Mi Jung Lim

Yu Jin Shin

Cheol Hyoung Park

The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same: The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same

The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same:  The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

Provided is a pharmaceutical composition for inhibiting apoptosis of neurons or neurodegeneration. The pharmaceutical composition effectively prevents or treats diseases related to apoptosis of neurons or neurodegeneration.

Pharmaceutical composition for inhibiting apoptosis of neuron or neurodegeneration

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Daejeon, South Korea

Jin Yong Chung