Sk Biopharmaceuticals Co., Ltd.

Jin Yong Chung

Ji Won Lee

Hye Kyung Min

Ji Yeon Kim

Ju Young Lee

Chan Mi Joung

Eun Ju Choi

Young Koo Jang

Cheol Young Maeng

Nahm Ryune Cho

Yong Je Shin

Hyo Jun Jung

Eun Ju Ryu

Soo Bong Cha

Yong Gil Kim

Jong Sil Park

Chun Eung Park

Seung Nam Han

Seung Mo Ham

Yeo Jin Yoon

Joo Young Park

Mi Jung Lim

In Suk Park

Cheol Hyoung Park

Joon Heo

Han Ju Yi

Young Soon Kang

Eun Hee Chae

Yu Jin Shin

Ki Ho Lee

The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same: The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same

The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same:  The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

Provided is a pharmaceutical composition for inhibiting apoptosis of neurons or neurodegeneration. The pharmaceutical composition effectively prevents or treats diseases related to apoptosis of neurons or neurodegeneration.

Pharmaceutical composition for inhibiting apoptosis of neuron or neurodegeneration

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Daejeon, South Korea

Jin Yong Chung