Glaceum, Inc.

Seoul National University

Erum Biotechnologies, Inc.

Sogang University Research Foundation

Imgt Co, Ltd.

Medicalip Co., Ltd.

Jin Wook Chung

Sang Ku Yoo

Ku Suk Kang

In Geun Jo

Jeong Ho Im

Ji Young Kim

Jin Young Kim

Sang Joon Park

Doo Hee Lee

Jin Mo Goo

Jin Sung Kim

Jung Hoon Kim

Sang Youn Lee

Hyun Cheol Kim

Sang-Ku Yoo

Yang Wook Kim

Eun Ah Jung

Jeong Ho Lim

The present invention aims to dramatically increase the effect of hepatic arterial chemoembolization by developing human serum albumin-based nanoparticles, which are bioproteins that effectively carry Adriamycin in place of Adriamycin, an anticancer agent used in hepatic arterial chemoembolization. The human serum albumin nanoparticles carrying the Adriamycin not only intensively infiltrate the drug effectively into the cells but also have a synergistic effect that can induce a long-term therapeutic effect by utilizing the effect of continuous drug release from the particles.

Composition for hepatic arterial chemoembolization using human serum albumin nanoparticles carrying anticancer agent, and method for producing same

The present invention relates to a method for synthesizing a 3-phenyl-2,8-dihydropyrano[2,3-f]chromene derivative, which may be usefully used for synthesizing a pyranochromenyl phenol derivative, and when the derivative is used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative may be effectively prepared.

Method for synthesizing 3-phenyl-2,8-dihydropyrano [2,3-f] chromene derivative

The present invention relates to pyranochromenylphenol derivatives having different efficacies depending on the direction of optical activity and a pharmaceutical composition including the same, and in the pyranochromenylphenol derivatives, an R-enantiomer has excellent anti-diabetic efficacy by suppressing a rise in blood sugar and an S-enantiomer has excellent anti-obesity efficacy by suppressing an increase in body weight.

Optically active pyranochromenyl phenol derivative and pharmaceutical composition comprising same

The present invention relates to a method for synthesizing a 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and an optical isomer thereof, and an intermediate Compound which may be used for the synthesis method, and when the method and the intermediate Compound are used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and the optical isomer thereof may be effectively synthesized.

3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and method for synthesizing optical isomer thereof

Method for synthesizing 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2.3-f]chromene derivative and optical isomer of thereof

A method of forming a transparent 3D object and a transparent 3D object formed by the method are provided. A transparent 3D object may be formed as follows. An internal structure of a 3D object is printed using a 3D printer based on a 3D image file having information about an internal region of the 3D object, and a mold, designed to form the 3D object and divided into at least two regions, is printed using the 3D printer based on the 3D image file. Then, the internal structure is combined with an inner region of the mold, and a transparent material is supplied to the mold. After the transparent material hardens, a transparent 3D object is obtained by removing the mold.

Method of forming transparent 3D object

Provided is an apparatus for generating 1-methylcyclopropene. The apparatus of the present invention may enable the immediate and convenient generation of 1-methylcyclopropene in a desired location using stable 1-methylcyclopropene precursors.

Apparatus for generating 1-methylcyclopropene

Provided is a method and apparatus for segmenting airways and pulmonary lobes. An image processing apparatus obtains a first candidate region of an airway from a three-dimensional (3D) human body image by using a region growing method, obtains a second candidate region of the airway based on a directionality of a change in signal intensity of voxels belonging to a lung region segmented from the 3D human body image, segments an airway region by removing noise based on similarity of a directionality of a change in signal intensity of voxels belonging to a third candidate region acquired by combining together the first and second candidate regions. Furthermore, the image processing apparatus segments a lung region from a 3D human body image by using a region growing method, obtains a fissure candidate group between pulmonary lobes based on a directionality of a change in signal intensity of voxels belonging to the lung region, reconstructs an image of the lung region including the fissure candidate group into an image viewed from a front side of a human body and generates a virtual fissure based on a fissure candidate group shown in the reconstructed image, and segments the pulmonary lobes by using the virtual fissure.

Method for extracting airways and pulmonary lobes and apparatus therefor

Provided are a pyranochromenyl phenol derivative, a pharmaceutically acceptable salt thereof, or a solvate thereof. Also provided is a pharmaceutical composition for preventing or treating metabolic syndrome or inflammatory disease comprising same. The present invention is efficacious in preventing or treating metabolic syndrome or inflammatory disease and is chemically stable.

Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease

Disclosed is a method for directly preparing in situ cyclopropenes for inhibiting ethylene action facilitating ripening and aging of plants via reaction of a cyclopropene precursor such as a compound of Formula (2) or Formula (3) with a fluoride (F) and immediately applying the same to plants, and an aryl group-containing 1-alkylcyclopropene of Formula (6) effective for inhibiting the action of ethylene.

Growing community of inventors

Seoul, South Korea

Jin Wook Chung