Danisco US Inc.

Jimmy Chan

Michael C Ward

Michael D Ward

Benjamin S Bower

Suzanne E Lantz

Thijs Kaper

Susan Mampusti Madrid

Jing Ge

Xiaogang Gu

Rachel E Muir

Steven Sungin Kim

Amr R Toppozada

Danfeng Song

Mingmin Song

William Throndset

Steven Sungjin Kim

Kirstin Y NosÉ Crotty

Meredith K Fujdala

Compositions and methods are provided for genome modification at a target site in the genome of a filamentous fungal cell. The methods and compositions are drawn to a guide polynucleotide/Cas endonuclease system for modifying or altering the target site. Aspects in which the filamentous fungal cell being modified has a defective non-homologous end joining pathway are also provided.

Fungal genome modification systems and methods of use

Compositions and methods are provided for genome modification at a target site in the genome of a fungal cell. The methods and compositions are drawn to a guide polynucleotide/Cas endonuclease system for promoting modification of the DNA sequence at a target site in a fungal host cell genome.

The invention provides a culture plate made from a polymer incorporating a culture component releasable into culture media in the well, methods of culturing a microorganisms in the culture plate, and a methods of making the culture plate.

Microtiter plates for controlled release of culture components to cell cultures

Growing community of inventors

Palo Alto, CA, United States of America

Jimmy Chan