Other

Varian Semiconductor Equipment Associates, Inc.

Jillian Reno

William Davis Lee

Mark R Amato

James P Bennett

Nick Ruebel

Susan L Michaud

Morgan Evans

Daniel J Raymond

Daniel Distaso

Stanislav S Todorov

Scott Penfold

Armin Huseinovic

Kyle Schmanke

Lou Wainwright

Edward Ivanov

Stephen Sledge

Lauri Reichert

The invention comprises a segmented rolling floor apparatus and method of use thereof, such as for use in a charged particle cancer therapy system. The segmented rolling floor comprises a first spool and a second spool, attached to opposite ends of the rolling floor, which cooperatively wind and unwind the rolling floor. The segmented rolling floor circumferentially surrounds a nozzle system penetrating through an aperture in the segmented rolling floor, where the nozzle system is used to deliver charged particles, from an accelerator, to a tumor of a patient. The rolling floor and nozzle systems move at respective rates maintaining the nozzle system in the aperture allowing for a safe/walkable floor while allowing treatment of the tumor as a gantry rotates the nozzle system and delivers protons to the tumor from positions above and below the floor.

Gantry charged particle nozzle system&#x2014;rolling floor interface apparatus and method of use thereof

The invention comprises a method and apparatus for treating a tumor, comprising the steps of: (1) a main controller sequentially delivering charged particles from a synchrotron along a first beam transport line, through a nozzle system, and to the tumor according to a current version of the radiation treatment plan; (2) concurrent with the step of delivering, generating an image of the tumor using an imaging system; (3) the main controller automatically generating an updated version of the radiation treatment plan using the image, the updated version of the radiation treatment plan becoming the current version of the radiation treatment plan; and (4) repeating the steps of: delivering grouped bunches of the charged particles, generating an image of the tumor, and automatically generating the updated or current version of the radiation treatment plan with optional intervening doctor approval.

Automated cancer therapy apparatus and method of use thereof

The invention comprises a method and apparatus for directing protons to a tumor, comprising the steps of: (1) holding a patient with a patient support; (2) providing an imaging system comprising: a rotatable unit at least partially surrounding an axial perimeter of the patient support, a translation guide rail, an imaging source attached to the rotatable unit, and an imaging detector attached to the rotatable unit; (3) translating and rotating the imaging source and the imaging detector relative to the patient support using the translation guide rail and the rotatable unit; and (4) providing an attachment section connected: on a first end to a robotic arm positioning system and on a second end to the patient support and the imaging system, the robotic arm positioning system repositioning, relative to a nozzle system linked to the synchrotron, the attachment system supporting the patient support system and the imaging system.

Integrated imaging-cancer treatment apparatus and method of use thereof

The invention comprises an apparatus and method of use thereof for using a single patient position during, optionally simultaneous, X-ray imaging and positively charged particle imaging, where imaging a tumor of a patient using X-rays and positively charged particles comprises the steps of: (1) generating an X-ray image using the X-rays directed from an X-ray source, through the patient, and to an X-ray detector, (2) generating a positively charged particle image: (a) using the positively charged particles directed from an exit nozzle, through the patient, through the X-ray detector, and to a scintillator, the scintillator emitting photons when struck by the positively charged particles and (b) generating the positively charged particle image of the tumor using a photon detector configured to detect the emitted photons, where the X-ray detector maintains a position between said the nozzle and the scintillator during the step of generating a positively charged particle image.

Simultaneous/single patient position X-ray and proton imaging apparatus and method of use thereof

The invention comprises a method for treating a tumor of a patient with positively charged particles in a treatment room, comprising the steps of: (1) controlling a cancer therapy treatment system with a main controller, the main controller comprising hardware and software; (2) generating at least one image of the tumor using at least one imaging system controlled by the main controller; (3) using the at least one image and a software coded set of radiation treatment directives, the main controller auto-generating a radiation treatment plan; and (4) the main controller auto-delivering the positively charged particles, via a beam transport system and a nozzle system, from a synchrotron to the tumor according to the radiation treatment plan.

Semi-automated cancer therapy treatment apparatus and method of use thereof

The invention comprises a method and apparatus for treating a tumor of a patient using positively charged particles, comprising the steps of: (1) providing an approved current version of a radiation treatment plan for treatment of the tumor using the positively charged particles; (2) implementing the current version of the radiation treatment plan using a cancer therapy system comprising a controller linked to a synchrotron; (3) upon identifying an object, using a set of fiducial indicators, in a treatment vector of the radiation treatment plan: generating a modified version of radiation treatment plan and receiving medical doctor approval of the modified version of the radiation treatment plan, the modified version of the radiation plan becoming the current version of the radiation treatment plan; and (4) repeating the steps of implementing and identifying until completion of treatment of the tumor using the positively charged particles.

Treatment beam path verification in a cancer therapy apparatus and method of use thereof

The invention comprises a method for generating a procedure for treating a tumor of a patient using positively charged particles, comprising the steps of: (1) providing a set of treatment goal specifications; (2) generating tomographic images of the tumor using a first set of groups of the positively charge particles delivered from a synchrotron; and (3) a computer implemented algorithm automatically generating a tumor radiation treatment plan, of the tumor using the positively charged particles, using the set of treatment goal specifications and the tomographic images. Optionally, the method automatically updates the radiation treatment plan upon: a detected movement of the tumor relative to surrounding patient constituents and/or upon detection of a previously unforeseen intervening object in a treatment beam path.

Automated radiation treatment plan development apparatus and method of use thereof

The invention comprises a method and apparatus for treating a tumor with protons using multiple beamline positions not having an isocenter, including the steps of: (1) delivering the protons from a synchrotron along a redirectable beam transport path to yield a plurality of incident vectors, each of the plurality of incident vectors directed toward the treatment room and (2) redirecting the protons traveling along each of the plurality of incident vectors, with an output nozzle, to the tumor, where a first vector, of the plurality of incident vectors, comprises a first direction intersecting the tumor and where a second vector, of the plurality of incident vectors, comprises a second direction passing by the tumor without entering the tumor. The step of redirecting directs the protons traveling along the first and second incident vectors, respectively, to a first and second path intersecting a front and the back of the tumor.

Multiple beamline position isocenterless positively charged particle cancer therapy apparatus and method of use thereof

The invention comprises a method and apparatus for determining a radiation beam treatment path to a tumor, comprising the steps of: (1) delivering charged particles from an accelerator, along a first beam transport path, through an output nozzle, and along a treatment path to the tumor relative to a calibrated reference beam path from the output nozzle toward a patient position and (2) prior to the step of delivering, a main controller verifying an unobstructed linear path of the treatment path using a set of fiducial indicators positioned at least: on a first element physically affixed and co-movable with the output nozzle and on a moveable object in the treatment room. Optionally, voxels of the treatment beam path and potentially obstructing objects are defined in the treatment room using an axis system relative to the calibrated reference beam path and a reference beam point.

Transformable charged particle beam path cancer therapy apparatus and method of use thereof

The invention comprises a method and apparatus for treating a tumor using positively charged particles having passed through an intervening object, comprising the steps of: predetermining an energy reduction of the positively charged particles resultant from the positively charged particles traversing the intervening object along a beam treatment path as a function of relative rotation of the patient and the beam treatment path; generating a radiation treatment plan adjusting energy of the positively charged particles delivered from the synchrotron to the intervening object to yield a desired beam treatment energy of the positively charged particles entering the tumor after compensating for the energy reduction; and optionally detecting a set of the positively charged particles after traversing the intervening object to yield a signal, where the signal is used with knowledge of energy of the positively charged particles exiting the synchrotron to pre-determine the energy reduction along the beam treatment path.

Intervening object compensating automated radiation treatment plan development apparatus and method of use thereof

The invention comprises a fiducial marker&#x2014;fiducial detector based treatment room position determination/positioning system apparatus and method of use thereof. A set of fiducial markers and fiducial detectors are used to mark/determine relative position of static and/or moveable objects in a treatment room using photons passing from the markers to the detectors. Further, position and orientation of at least one of the objects is calibrated to a reference line, such as a zero-offset beam treatment line passing through an exit nozzle, which yields a relative position of each fiducially marked object in the treatment room. Treatment calculations are subsequently determined using the reference line and/or points thereon. The treatment calculations are optionally and preferably performed without use of an isocenter point, such as a central point about which a treatment room gantry rotates, which eliminates mechanical errors associated with the isocenter point being an isocenter volume in practice.

Fiducial marker / cancer imaging and treatment apparatus and method of use thereof

Fiducial marker/cancer imaging and treatment apparatus and method of use thereof

The invention comprises a method and apparatus for treating a tumor, comprising the steps of: (1) a main controller implementing an initial radiation treatment plan, as a current radiation treatment plan, using positively charged particles delivered from a synchrotron, along a beam transport line, through a nozzle system proximate the treatment room, and into the tumor; (2) concurrent with the step of implementing, imaging the tumor, such as with protons, to generate a current image; (3) upon detection of movement of the tumor relative to surrounding constituents of the patient using the current image, the main controller, using computer implemented code, automatically generating an updated treatment plan, the updated treatment plan becoming the current radiation treatment plan; and (4) repeating the steps of implementing, imaging, and generating an updated treatment plan at least n times, where n is a positive integer of at least one.

Auto-updated and implemented radiation treatment plan apparatus and method of use thereof

Methods for the selective processing of the outer portion of a workpiece are disclosed. The outer portion is processed by directing an ion beam toward the workpiece, where the ion beam extends beyond the outer edge of the workpiece at two locations. The workpiece is then rotated relative to the ion beam about the center so that all regions of the outer portion are exposed to the ion beam. The workpiece may be rotated an integral number of rotations. The ion beam may perform any process, such as ion implantation, etching or deposition. The outer portion may be an annular ring having an outer diameter equal to that of the workpiece and having a width of 1 to 30 millimeters. The rotation of the workpiece may be aligned with a notch on the outer edge of the workpiece.

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Beverly, MA, United States of America

Jillian Reno