Panmira Pharmaceuticals, LLC

Amira Pharmaceuticals, Inc.

Pharmakea, Inc.

Sabre Therapeutics LLC

Df 2024 IP Acquisition, LLC

Jillian Frances Evans

John Howard Hutchinson

Petpiboon Peppi Prasit

Mark Moran

Nicholas Simon Stock

Jasmine Eleanor Zunic

Jeannie M Arruda

Yiwei Li

Gretchen Bain

Brian Andrew Stearns

Mustapha Haddach

Jeffrey Roger Roppe

David Gregory Lonergan

Deidre A MacKenna

David Lonergan

Described herein are methods and compositions for the treatment of conditions, diseases, or disorders associated with autotaxin activity. The methods and compositions disclosed herein include the use of at least one autotaxin inhibitor compound.

Autotaxin inhibitors and uses thereof

Described herein is the use of a LOXL2 inhibitor in the treatment or prevention of conditions, diseases, or disorders associated with LOXL2 activity.

Uses of a lysyl oxidase-like 2 inhibitor

Described herein are methods and compositions for treatment or prevention of metabolic disorder(s) in an individual. The methods and compositions disclosed herein include the use of at least one autotaxin inhibitor compound.

Methods for the treatment of metabolic disorders by a selective small molecule autotaxin inhibitor

Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.

5-lipoxygenase-activating protein (FLAP) inhibitors

A method for treating a human comprises administering a therapeutically effective amount of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid or a pharmaceutically acceptable salt or a pharmaceutically acceptable N-oxide thereof, to the human in need.

5-lipdxygenase-activating protein (FLAP) inhibitors

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San Diego, CA, United States of America

Jillian Frances Evans