Beijing Medisan Technology Co., Ltd

Harbin Medisan Pharmaceutical Co., Ltd.

Ningbo Violet Lighting Electric Co., Ltd.

Jiguo Sun

Fan Yang

Yan Wang

Lei Ji

Jin Cui

Ailing Wang

Mingxin Wang

Jinai Liu

Hong Hu

Li Ju

Hanjun Huang

Yuehua Chen

Gang Wang

The present invention relates to a norepinephrine and selective serotonin receptor blocker and the use thereof. The norepinephrine and selective serotonin receptor blocker is a compound of formula I, or isomers, pharmaceutically acceptable salts or solvates thereof, wherein R1 is selected from the group consisting of C1-6 alkyl, C1-6 alkoxy, C6-10 aralkyl, C6-10 arylalkoxy, C1-6 haloalkyl and C1-6 haloalkoxy; and R2 is one or more groups each independently selected from the group consisting of hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, nitro, cyano, amino, hydroxyl, C1-6 haloalkyl, and C1-6 haloalkoxy. R3 is one or more groups each independently selected from the group consisting of hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, nitro, cyano, amino, hydroxyl, C1-6 haloalkyl, and C1-6 haloalkoxy. The compound of the present invention is effective norepinephrine and selective serotonin receptor blocker. 

Norepinephrine and selective serotonin receptor blocker and use thereof

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Beijing, China

Jiguo Sun