Ningxia Eppen Biotech Co., Ltd

Jifu Wen

Yun Zhang

Yong Fang Liang

Qian Jack Liu

Tingyi Wen

Shuwen Liu

Xiuling Shang

Qian Liu

The present invention discloses anengineering bacteria producing 1,5pentanediamine through a whole cell catalysis and its application. The engineering bacteria according to the present invention, is() strain B or its derivative strains with the overexpression of a lysine decarboxylase gene and a proper expression of a lysinecadaverine antiporter gene cadB. The engineering bacteria according to the present invention is the engineering bacteria producing 1,5pentanediamine through the whole cell catalysis constructed fromB derivative strains, which has an overexpression of a lysine decarboxylase gene cadA and a proper expression of the lysinecadaverine antiporter gene cadB; The present invention further discloses a method of producing a 1,5pentanediamine catalyzed by the engineering bacteria, the yield and production intensity of 1,5pentanediamine in biobased production could be significantly improved through the method, hence it could be applied to mass production and convenient for extending applications.

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Beijing, China

Jifu Wen