Lg Electronics Inc.

Samsung Display Co., Ltd.

Voronoi Inc.

Korea Institute of Science and Technology

Dana-farber-cancer Institute Inc.

Electronics and Telecommunications Research Institute

Jieun Choi

Kyoungho Lee

Sanghyuk Son

Taeyoon Kim

Kunyoung Lee

Jongsu Lee

Jungwoo Lee

Chungook Chong

Younggu Lee

Hyungho Park

Juncheol Shin

Jeongtaek Park

Jongbaek Seon

Jaehak Lee

Inho Choi

Yanghwa Lee

Yongsung Park

Woojin Kim

Hojung Kim

Kyungchan Chae

Jaehoon Lee

Yongmin Kim

Kyuchun Choi

Sungwoo Jung

Nathanael Schiander Gray

So Young Lee

Hoon Sik Kim

Hyoung-Juhn Kim

Jong Hyun Jang

Hyunjung Kim

Sung Jong Yoo

Hyun Seo Park

Jong Min Lee

Hee-Young Park

Minsu Lee

Kwangho Lee

Jaeseung Choi

HyunJung Kim

Jinhyun Kim

Kyungho Lee

Hyuckju Kwon

Unchang Jeong

Hooncheol Jeon

JinUk Kim

Namdoo Kim

Daegeun Son

Jungmin Shim

Nam-Hyun Kim

Hwangeun Choi

Sunyoung Moon

Jungbeom Son

Daekwon Kim

Eunhwa Ko

Woongi Kil

Ahram Kim

Hayoung Kim

John M Hatcher

Jongsun Jeon

Jingak Jang

Youhan Moon

Hwan Oh Kim

Jieun Kim

Bora Seo

Wansu Youn

Sun-Hwa Lee

Inho Hwang

Miyoung Sim

Heesun Park

Seongkyeol Hong

Seungwoo Rho

HuiRae Cho

Sohyun Chung

Myungho Jung

Heesun Ryu

Jungyeon Yun

Dahoon Ma

Hyeonho Jeon

Hyunkyung Kim

Yeonsil Kim

Geunchul Park

Chan-Yeol Park

Jing Young Kim

YoungHyoun Kwon

Jaeki Lee

Jeon Hooncheol

Disclosed are compounds that possess inhibitory activity against LRRK2. Also disclosed are pharmaceutical compositions containing the compounds and methods of using the compounds to treat neurodegenerative diseases and disorders such as Parkinson's disease and brain cancer (e.g., gliomas and glioblastomas).

Pyrrolopyrimidine inhibitors of wild-type and mutant forms of LRRK2

A display panel includes a base layer including a display area and a non-display area, a repair circuit disposed in the non-display area, a pixel disposed in the display area and including a pixel circuit and a light emitting element electrically connected to the pixel circuit, and a repair line electrically connecting the repair circuit to the pixel. The pixel circuit includes a silicon transistor including a silicon semiconductor pattern and a first gate disposed on the silicon semiconductor pattern, an oxide transistor including a light shielding pattern disposed on the first gate and disposed on the same layer as the repair line, an oxide semiconductor pattern disposed on the light shielding pattern, and a second gate disposed on the oxide semiconductor pattern, and a bridge electrode electrically connected to the light emitting element and the silicon transistor.

Display panel with a repair circuit

A display device includes: a light emitting element; a first driving transistor between a first node and the light emitting element; a second driving transistor between the first node and the light emitting element; a switching transistor between a data line and the first node; a first compensation transistor between a first control electrode of the first driving transistor and a second node, and configured to receive a first compensation scan signal; a second compensation transistor between a second control electrode of the second driving transistor and the second node, and configured to receive a second compensation scan signal; a first initialization transistor between the first control electrode of the first driving transistor and a first initialization voltage line; and a second initialization transistor between the second control electrode of the second driving transistor and a second initialization voltage line.

Display device

Disclosed are compounds that possess inhibitory activity against LRRK2. Also disclosed are pharmaceutical compositions containing the compounds and methods of using the compounds to treat diseases and disorders including neurodegenerative diseases and disorders such as Parkinson's disease, and brain cancer (e.g., gliomas and glioblastomas).

Azaindole inhibitors of wild-type and mutant forms of LRRK2

A mobile robot of the present disclosure includes: a traveling unit configured to move a main body; a lidar sensor configured to acquire terrain information outside the main body; a camera sensor configured to acquire an image outside the main body; and a controller configured to fuse the image and a detection signal of the lidar sensor to select a front edge for the next movement and set a target location of the next movement at the front edge to perform mapping travelling. Therefore, in a situation where there is no map, the mobile robot can provide an accurate map with a minimum speed change when travelling while drawing the map.

Mobile robot using artificial intelligence and controlling method thereof

A display panel includes: a substrate including a first area, a second area, and a third area; a stacked structure corresponding to a plurality of display elements in the second area, the stacked structure including a pixel electrode, an opposite electrode, and an intermediate layer between the pixel electrode and the opposite electrode; and a plurality of grooves in the third area, wherein the stacked structure includes at least one organic material layer that is disconnected by the plurality of grooves, at least one groove of the plurality of grooves is defined in a first multi-layer including a first lower layer and a first upper layer, and at least one of the first lower layer and the first upper layer includes a plurality of sub-layers.

Display panel

[Summary] The present invention relates to a pyrrolopyridine derivative and a pharmaceutical composition comprising the same as an active ingredient for prevention or treatment of a protein kinase-related disease. The pyrrolopyridine derivative has excellent inhibitory activity against various protein kinases including LRRK2, DYRK1, and CLK1 and exhibits an excellent suppressive effect on the growth of triple-negative breast cancer cells. A pharmaceutical composition comprising the same as an active ingredient can be advantageously used for treating or preventing protein kinase-related diseases, inter alia, cancers, degenerative brain diseases, and inflammatory diseases, and specifically for treating triple-negative breast cancer.

Pyrrolopyridine derivative and use thereof in prevention and treatment of protein kinase-related disease

A display device includes: a substrate having an opening; a plurality of display elements at a display area adjacent to the opening, the plurality of display elements each including a pixel electrode, an opposite electrode, and an intermediate layer between the pixel electrode and the opposite electrode; and a metal stacked structure between the opening and the display area, and including: a first sub-metal layer having a first hole; and a second sub-metal layer under the first sub-metal layer and having a second hole, the second hole overlapping with the first hole and having a width greater than a width of the first hole.

Display device including sub-metal layers and tip

Provided is a mobile robot including a traveling unit configured to move a main body, a light detection and ranging (LiDAR) sensor configured to acquire external geometry information of the main body, and a controller configured to create node data based on LiDAR data sensed by the LiDAR sensor, to create grid map based on the LiDAR data and the node data, to create first map data based on the node data, to update the grid map based on the first map data, and to image-process the updated grid map to create second map data, where a map may be quickly and safely created without an environmental restriction, by effectively combining a node-based map creating method and a grid-based map creating method.

Mobile robot and control method thereof

A display device includes a plurality of pixels, a dummy pixel, and a repair line, wherein the plurality of pixels may include a first subpixel including a first pixel circuit connected with a first initialization voltage line through which a first initialization voltage is provided, and a first light emitting element, and a second subpixel including a second pixel circuit connected with a second initialization voltage line through which a second initialization voltage different from the first initialization voltage is provided, and a second light emitting element, wherein the dummy pixel may include a first transistor connectable with the repair line and connected with the first initialization voltage line, a second transistor connectable with the repair line and connected with the second initialization voltage line, and a dummy pixel circuit connectable with the repair line.

Display device and display device repair method

A sterilization case includes a case body having a seating surface configured to seat an object to be sterilized, a case cover that is coupled to the case body, the case cover and the case body defining an accommodation space that is configured to accommodate therein the object to be sterilized, a sterilization module that is provided at the case body and configured to sterilize the object to be sterilized, and a reflective pattern provided at an inner surface of the case cover and configured to reflect ultraviolet light emitted from the sterilization module onto a surface of the object to be sterilized.

Sterilization case

A moving robot includes: a sensor to acquire terrain information; a memory to store node data for at least one node; and a controller, and the controller determines whether at least one open movement direction exists among a plurality of movement directions, based on sensing data and the node data, generates a new node in the node data when at least one open movement direction exists, determines any one of the open movement directions as a traveling direction for the robot, determines whether at least one of the nodes needs to be updated exists, based on the node data when the open movement direction does not exist, controls the moving robot to move to one of the nodes that need to be updated, and generates of a map including the at least one node, based on the node data, when the node that needs to be updated does not exist.

Moving robot and control method thereof

A moving robot including: a lidar sensor to acquire terrain information; a memory to store node data nodes; and a controller to determine whether at least one open movement direction exists based on sensing data of the lidar sensor and the node data, to generate a new node in the node data and add the generated node to a node group, to determine any of the open movement directions as a movement direction, to control the robot to travels an area corresponding to the node group, to control a suction unit to suck foreign matter around the main body when traveling in the node group, to initialize the node group, to determine whether at least one node is to be updated, moving the robot to any one of the nodes to be updated, and to complete generation of a map.

Growing community of inventors

Seoul, South Korea

Jieun Choi