Cisco Technology, Inc.

Chinese Academy of Medical Sciences

Beijing Tide Pharmaceutical Co., Ltd.

Baidu Online Network Technology (beijing) Co., Ltd.

Hi-p International Limited

Jie Meng

Kai Liu

Hongjun Wang

Jian Qiang Liu

Zewang Feng

Liying Zhou

Yanping Zhao

Yanan Liu

Haiyan Xu

Tao Wen

Jianmei Pang

Huai Huang

Xuelian Liu

Wenwen Dong

Nana Tian

Xichao Chen

Shenzhen Fu

Tao Wang

Jun Zhang

Bing Han

Xuan Wang

De Fu Li

Yong Lu

Rundong Huang

Rui Lu

Shuzhan Chen

Jingfeng Zhang

Yangyang Ge

Dashuai Zhang

Liang Hong

Ross Alcazar

CheungLing Cheng

Doudou Yan

The present invention relates to a salt of 5-((2-ethynyl-5-isopropylpyridin-4-yl)oxy)pyrimidine-2,4-diamine and a solid form thereof, a method for preparing the solid form and a pharmaceutical composition comprising the solid form, as well as a use of the solid form for preventing or treating diseases modulated by P2X3 and/or P2X2/3 receptor antagonists.

Salt of diaminopyrimidine compounds, and solid form thereof, preparation method therefor and use thereof

The present invention relates to a solid form of 5-((2-ethynyl-5-isopropylpyridin-4-yl)oxy)pyrimidine-2,4-diamine or a hydrate thereof, a method for preparing the solid form, a pharmaceutical composition comprising the solid form, and a use of the solid form for the prevention or treatment of a disease modulated by P2X3 and/or P2X2/3 receptor antagonists.

Solid form of diaminopyrimidine compound or hydrate thereof, preparation method therefor, and application thereof

The present invention discloses a dual-drug co-delivery system, a preparation method therefor and use thereof, the dual-drug co-delivery system being prepared from raw materials comprising a block copolymer, Homoharringtonine and Doxorubicin hydrochloride. The dual-drug co-delivery system provided by the present invention has a stronger killing effect on various hematologic tumors and solid tumor cells, can provide a feasible drug delivery system for inhibiting tumor growth and leukemia treatment, and has broad prospects.

Dual-drug co-delivery system, preparation method therefor and use thereof

Disclosed is the use of a water-soluble realgar solid dispersion in the preparation of an erythroid differentiation inducer for bone marrow hematopoietic stem cells and/or bone marrow hematopoietic progenitor cells. The water-soluble realgar solid dispersion is prepared from raw materials comprising 1 part by weight of realgar, 1-20 parts by weight of a polymer, and 0-5 parts by weight of a surfactant. The water-soluble realgar solid dispersion can induce bone marrow hematopoietic stem and/or progenitor cells to be differentiated into red blood cells, promote the accumulation of red blood cells in bone marrow cells, effectively alleviate the decrease in the number of red blood cells caused by the suppression of the erythroid differentiation of bone marrow hematopoietic stem and/or progenitor cells, improve anemia caused by hematopoietic failure, and protect bone marrow cells from the killing effect.

Use of water-soluble realgar solid dispersion in preparation of erythroid differentiation inducer for bone marrow hematopoietic stem cells and/or bone marrow hematopoietic progenitor cells

The present disclosure provides a method and apparatus for building pages, an apparatus and a non-volatile computer storage medium. According to embodiments of the present disclosure, the initial document content of the page to be published is obtained so that page resources of the page to be published are generated according to the document arrangement information and the initial document content. Manual operations are not needed. This enables simple operations, a short operation duration and a high correctness rate, and thereby improves the page-building efficiency and reliability.

Method and apparatus for building pages, apparatus and non-volatile computer storage medium

Techniques are generally directed to selective reestablishment of Internet Protocol (IP) connectivity between a cable modem and a cable modem termination system (CMTS). IP connectivity between the cable modem and the CMTS is initially established through execution of a plurality of connectivity steps. After IP connectivity is lost, the cable modem determines which of the plurality of connectivity steps are desired for use in reestablishing IP connectivity, and sends a message to the CMTS indicating the desired IP connectivity step. The CMTS determines if the desired connectivity steps identified in the message may be used to reestablish IP connectivity, and sends a response message to the cable modem indicating if the desired connectivity steps may be used. IP connectivity is then reestablished using at least the desired connectivity steps.

Selective reestablishment of cable modem internet protocol connectivity

One embodiment of the invention includes a coax media converter (CMC) system communicatively coupled to at least one modem in a network system. The system includes a frequency reference configured to generate a clock signal in a local time domain. The system also includes a scheduling processor configured to extract a bandwidth allocation message from a data stream and to re-stamp each of at least one timestamp in the bandwidth allocation message in the local time domain based on the clock signal to generate a corresponding updated bandwidth allocation message comprising a respective at least one re-stamped timestamp. The system further includes a downstream physical interface configured to transmit the updated bandwidth allocation message to the at least one modem to schedule upstream burst transmissions from the respective at least modem based on the at least one re-stamped timestamp.

Network system time domain re-stamping

Techniques are provided herein for tagging configurable objects. The configurable object is part of a cable system and is configured to be managed by a cable modem termination system (CMTS). In response to determining that a tag rule matches one or more properties of the configurable object, the first tag is associated with the configurable object. A record of the configurable object and the associated tag is generated or stored within the CMTS.

Classifying objects on a cable modem termination system using tagging

The present invention relates to insert molding a glass lens or an inorganic material into a front housing unit. The glass lens or an inorganic material is aligned within the front housing unit so that it lies within the inside of the front housing unit. A thermobond adhesive or an adhesive promoter is applied onto the glass lens or the inorganic material. During molding a molten resin is injected into the space formed between the glass lens or the inorganic material and the front housing unit and flows around the glass lens or the inorganic material activating and liquefying the adhesive promoter or the thermobond adhesive and forming an insert molded part.

Method for insert molding glass or an inorganic material

Growing community of inventors

Beijing, China

Jie Meng