Zhejiang University

Hangzhou Normal University

Jiayun Xu

Xingqian Ye

Shiguo Chen

Huan Cheng

Junqiu Liu

Jianle Chen

Ruizhen Tian

Yijia Li

A method for promoting the solubility of rhamnogalacturonan I (RG-I) pectin based on polysaccharide interaction is provided. The method includes the following steps: adding an aqueous solution of negatively charged polysaccharides to an RG-I pectin extract, mixing uniformly, adjusting the potential of Hydrogen (pH) of the compound to 3-7, performing ethanol precipitation to obtain a precipitate; washing the precipitate, followed by drying and crushing to obtain a polysaccharide-pectin compound; where the RG-I pectin extract is obtained by extracting orange peel powder with dilute hydrochloric acid.

Method for promoting solubility of RG-I pectin based on polysaccharide interaction

A multi-enzyme cascade antioxidant nano HOF and preparation method and application thereof are provided. The present invention discloses a nano HOF based on selenium-containing ligand for the first time, the nano HOF does not contain metal and has good biocompatibility, which is a universal loading platform, and has high porosity, acid and alkali resistance and thermal stability, and is size-tunable, it can coat various types of enzymes at the same time, stabilize the conformation of the enzyme through the confinement effect, the high porosity can not only provide enough space for the enzyme, but also facilitate the transport of substances and the play of catalytic properties of the enzyme, 85-90% of the activity of the coated enzyme can be maintained, ROS can be effectively scavenged through the cascade catalysis between various enzymes, which provides a new idea for the construction of bio-friendly antioxidants.

Selenium-containing nano HOF, antioxidant nanozyme, preparation method and application thereof

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Hangzhou, China

Jiayun Xu