Purdue Research Foundation

The United States of America, As Represented by the Secretary, Department of Health and Human Services

The Scripps Research Institute

Jiayin Shen

Philip Stewart Low

Dimiter Stanchev Dimitrov

Yang Feng

Peter G Schultz

Pengyu Yang

Chanhyuk Kim

Jennifer Ma

Jun Y Axup

Hwayoung Yun

Methods, compositions and uses are provided for bispecific antibodies comprising one or more unnatural amino acids. The bispecific antibodies may bind to two or more different receptors, co-receptors, antigens, or cell markers on one or more cells. The bispecific antibodies may be used to treat a disease or condition (e.g., cancer, autoimmune disease, pathogenic infection, inflammatory disease). The bispecific antibodies may be used to modulate (e.g., stimulate or suppress) an immune response.

Targeting agent antibody conjugates and uses thereof

Human anti-human folate receptor beta antibodies and antigen-binding fragments thereof are described, as well as methods of using such antibodies and fragments to treat inflammatory disorders or cancers expressing cell surface FR&#x3b2;.

Anti-human folate receptor beta antibodies and methods of use

Human anti-human folate receptor beta (FR&#x3b2;) antibodies and antigen-binding fragments thereof are described, as well as methods of using such antibodies and fragments to treat inflammatory disorders or cancers expressing cell surface FR&#x3b2;.

Growing community of inventors

San Diego, CA, United States of America

Jiayin Shen