Sunshine Lake Pharma Co., Ltd.

Jiaping Wen

Gang Chen

Zheng Gu

Yonggang Wei

Wuyong Wu

Panpan Kang

Zongyuan Zhang

Pengcho Tang

Guozhi Zhu

Mingyun Yuan

Yincai Wang

Heran Wang

Yonghua Lu

Chengsheng Lan

Kangzhi Ye

Guizhuan Su

Guanpeng Qiu

The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in general formula (I), and to the preparation method therefor and pharmaceutical compositions comprising the derivatives, and to the use thereof as a therapeutical agent, especially as a DPP-IV inhibitor. The definition of each substituent in formula (I) is the same as the definition in the description. 

Hexahydropentaleno derivatives, preparation method and use in medicine thereof

Disclosed are glucopyranosyl derivatives used as sodium dependent glucose cotransporters (SGLTs) inhibitors, intermediates or preparation processes thereof, and pharmaceutical uses thereof, especially glucopyranosyl derivatives represented by Formula (I), or pharmaceutically acceptable salts or all stereoisomers thereof, pharmaceutical compositions containing these derivatives and their uses for treatment of diabetes and diabetes-related diseases. 

Glucopyranosyl derivatives and their uses in medicine

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Dongguan, China

Jiaping Wen