Shanghai Bilibili Technology Co., Ltd.

Zhejiang Huahai Pharmaceutical Co., Ltd.

Shanghai Aobo Pharmtech, Inc., Ltd.

Jianping Lin

Luning Huang

Hong Gu

Chao Huang

Anping Tao

Xiaowen Guo

Wenjing Zhang

Yuanbing Guo

Xiao Zhang

Xiaofei Gao

This application provides techniques of generating an audio resource pool based on extracting audio from target videos. The techniques comprise obtaining target videos; determining at least one to-be-processed video from the target videos based on audio features of the target videos; extracting audio from the at least one to-be-processed video; and generating an audio resource pool based on the extracted audio.

Video processing method and apparatus

The present invention relates to a synthesis process of suvorexant, novel compounds represented by formulas II, III, IV or V, or salts thereof for preparing suvorexant, and a method for preparing the intermediates. The preparation method uses a chiral starting material to synthesize chiral compounds represented by formulas II, III, IV or V, the compounds obtained being used for synthesizing the suvorexant. The preparation method has the advantages of simple operation, low cost, mild reaction conditions, simple post-treatment, easy to purify, high yield, high ee value for the product, and easy to industrialize. In the reaction route shown, R represents benzyl, allyl or 1-phenethyl, or optionally substituted benzyl at the 2 position to 6 position, such as 4-methoxybenzyl, 4-nitrobenzyl, 2-methylbenzyl, 4-chlorobenzyl or 3-fluorobenzyl. 

Suvorexant intermediate and preparation method thereof

Growing community of inventors

Shanghai, China

Jianping Lin