Sph No. 1 Biochemical & Pharmaceutical Co., Ltd.

Shanghai Ziyuan Pharmaceutical Co., Ltd.

Jianli Huo

Zhigang Zhang

Liuqing Yang

Jinguo Ding

Zhenhui Huang

Xinlei Zhu

Disclosed are a crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form, and a preparation method and a use thereof. In an X-ray powder diffraction pattern using Cu-K&#x3b1; as a source of radiation, the crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form has characteristic peaks at positions where diffraction angles 2&#x3b8; are equal to 12.3&#xb0;&#xb1;0.2&#xb0;, 17.6&#xb0;&#xb1;0.2&#xb0;, 21.4&#xb0;&#xb1;0.2&#xb0;, 24.7&#xb0;&#xb1;0.2&#xb0;, 25.3&#xb0;&#xb1;0.2&#xb0; and 27.8&#xb0;&#xb1;0.2&#xb0;. The crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form of the present invention has a high purity, and good stability; the preparation method is simple and convenient, has good reproducibility, and is easy to industrially popularize and apply.

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Shanghai, China

Jianli Huo