Eli Lilly and Company

Purdue Research Foundation

Rtx Bbn Technologies, Inc.

Jiangshan Wang

Rahim Rahimi

Jose Fernando Waimin Almendares

Sina Nejati

Jordan Seville

Mohit Singh Verma

Mike Gavin

Mohit Verma

Darby Mcchesney

Frank M Laduca

Murali Kannan Maruthamuthu

Andres Dextre

Passive devices for non-invasive gastrointestinal (GI) sampling are disclosed. In some embodiments, a device includes a capsule housing containing an absorbent sampling hydrogel. The capsule may be ingested by a patient and subsequently travel through the GI tract. Once the capsule reaches a desired location in the GI tract, GI fluid may flow into the capsule through a sampling aperture of the capsule. The fluid may be absorbed by and stored within the sampling hydrogel for subsequent analysis, and the absorption of the fluid may cause the sampling hydrogel to expand within the capsule. The capsule may further include a sealing member positioned between the sampling hydrogel and the sampling aperture, and the expansion of the sampling hydrogel may press the sealing member against the sampling aperture to seal the capsule.

Capsule for gastrointestinal sampling

Growing community of inventors

West Lafayette, IN, United States of America

Jiangshan Wang