Ascensia Diabetes Care Holdings Ag

Bayer Healthcare LLC

Jiangfeng Fei

Raeann Gifford

Yuan Wang

William Chiang

Stuart Green

Frank Kerrigan

Hoi-Cheong Steve Sun

Serban F Peteu

Craig Robson

Howard Easterfield

Narasinha C Parasnis

Mu Wu

Swetha Chinnayelka

Jeffery S Reynolds

Steven C Charlton

Hualin Jiang

Paul M Ripley

Henry C Arndt

Stanley A Telson

Steven Fowler

A non-leaching mediator may include a polymer having a polymeric backbone, and a plurality of phenothiazine groups bonded to the polymeric backbone. The plurality of phenothiazine groups may include at least one of a phenothiazine group having the general formula (IV): and salts thereof, where n is about 9 and 'R' represents the polymeric backbone to which the phenothiazine group is bonded, and a phenothiazine group having the general formula (V): and salts thereof, where n is about 9 and 'R' represents the polymeric backbone to which the phenothiazine group is bonded.

Polymer comprising a plurality of phenothiazine groups and methods of making the same

An electrochemical test sensor for detecting the concentration of an analyte in a fluid sample. The electrochemical test sensor includes a housing that has a first end and a second opposing end. The housing includes an opening at the first end to receive a fluid test sample. An electrode assembly includes a substrate, a working electrode, a counter electrode and a reagent. The substrate has a first surface and an opposing second surface. The working electrode is disposed on the first surface of the substrate, and the counter electrode is disposed on the second surface of the substrate. The electrode assembly is positioned within the housing to define a reaction channel. The electrochemical test sensor may be used with a removable lancet mechanism or integrated within a lancet mechanism to form one integral unit.

Electrochemical test sensor

An analyte sensor is provided that comprises a substrate which includes a semiconductor material. Embodiments may include a core of a conductive material, and a cladding of a semiconductor material, in which the cladding may form at least a portion of a conducting path for a working electrode of the analyte sensor. Method of manufacturing and using the analyte sensor are described, as are numerous other aspects.

Semiconductor based analyte sensors and methods

In some aspects, an analyte sensor is provided for detecting an analyte concentration level in a bio-fluid sample. The analyte sensor may include one or more conductors received in a hollow portion of a hollow member. The first conductor may be made, at least in part, of a semiconductor material and an active region may be provided in contact with at least the first conductor. The analyte sensor may, in one aspect, include a lancet and an integrated sensor. Manufacturing methods and apparatus and systems utilizing the analyte sensors are provided, as are numerous other aspects.

Analyte sensors, systems, testing apparatus and manufacturing methods

Integrated lancet/electrochemical test sensor assembly

A test meter system for testing a characteristic of a fluid, the test meter system including a test meter having a housing with an opening adapted to accept a test strip, an interrogation coil within the housing, a pick-up coil within the housing, and a test strip including at least one magneto-elastic-resonance sensor. When the test strip is within the opening, the interrogation coil may utilize magneto-elastic-resonance technology to interrogate the magneto-elastic-resonance sensor and the pick-up coil may be used to sense a resultant oscillation frequency of the magneto-elastic-resonance sensor, the resultant oscillation frequency associated with the characteristic. The test strip may include a plurality of sensors. The sensors may be coated with a coating sensitive to a characteristic of the fluid, where the interrogation reveals information about the fluid characteristic.

Test strip with magneto-elastic-resonance sensor

A non-leaching mediator may include a polymer comprising the general formula (VIII): and salts thereof, where R' is an organic group, m is 0 or 1, n is about 9, and x and y independently are an integer from 1 to 10,000.

In some aspects, an analyte sensor is provided for obtaining and detecting an analyte concentration level in a bio-fluid sample. The analyte sensor has a sensor body including a semiconductor material, an active region coupled to the sensor body, and a lancet provided on the analyte sensor. The conductor may include a fiber having a core of a conductive material and a semiconductor cladding surrounding the core. Numerous other aspects are provided.

Lancet analyte sensors and methods of manufacturing

The present invention is directed to phenothiazine-based macromonomer compounds and methods of making the same. 

Radically polymerizable phenothiazine macromonomer for use in the coating of medical devices

The use of electrical impedance spectroscopy to adjust calibration settings in an in vivo monitoring system, such as an in vivo continuous glucose monitoring sensor. The adjustments can compensate for the condition of the sensor membrane in vivo.

Growing community of inventors

Sleepy Hollow, NY, United States of America

Jiangfeng Fei