Verance Corporation

Crinetics Pharmaceuticals, Inc.

Asml Netherlands B.v.

Jian Zhao

Joseph M Winograd

Rade Petrovic

Yunfei Zhu

Shimiao Wang

Sangdon Han

Sun Hee Kim

Mi Chen

Guillaume Mercier

Joseph Pontillo

Zhiyong Chen

Patrick George Downes

Jayachandra P Reddy

Tetsuya Ishikawa

Julia Ann Kenyon

Michael George Kiefer

Madhukar Kota

Uttam Dash

Mahmoud Mirmehrabi

Described herein are compounds that are melanocortin subtype-2 receptor (MC2R) modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of MC2R activity.

Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof

A method for embedding video watermarks. Areas of poor visual quality in a video content having embedded watermarks ar determined. The watermark symbols replace pixels in the video content with pixels in which the luma values are modulated such the luma value for a 0 bit renders as black and the luma value for a 1 bit renders a shade of gray. The luma value for the 1 bit level is reduced in those areas determined to have poor visual quality. Areas of poor visual quality may be determined by analyzing the luma values of pixels of the video content immediately adjacent to and below a particular watermark symbol to derive an adjacent brightness parameter that represents the perceptual brightness of the surrounding video content. The reduction of the luma value may be achieved by setting the 1 bit luma for a particular watermark symbol to be perceptually less bright than the adjacent brightness parameter.

Psycho-visual-model based video watermark gain adaptation

Described herein are somatostatin subtype-2 receptor (SST2R) targeted therapeutics that target tumor cells expressing SST2R and their use in the treatment of cancer.

Somatostatin subtype-2 receptor (SST2R) targeted therapeutics and uses thereof

Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.

Somatostatin modulators and uses thereof

Nonpeptide somatostatin type 5 receptor agonists and uses thereof

Content screening operations, which can include watermark extraction and the application of content usage enforcement actions, may be organized such that some or all of the operations can be conducted by different devices that are connected via connectors such as HDMI (High-Definition Multimedia Interface (HDMI), analog composite video, DVI (Digital Visual Interface), SDI (Serial Digital Interface), DisplayPort, or networked via Ethernet or wireless. Authentication and encryption methods are disclosed that can be used to establish the trust and secure communication between devices that conduct collaborative content screening. Delegation architecture may be based on ascertained screening capabilities of the sink device wherein the source device verifies that the sink device is capable and trusted to perform partial or whole screening operations delegated by the source. Alternatively, delegation architecture may be based on ascertained screening capabilities of the source device wherein the sink device verifies that the source device is capable and trusted to provide correct content credential and content use policy ('content credential') that is needed for the sink device to determine whether content screening should be performed, and if yes, what content screening operations should be performed.

Device authentication in collaborative content screening

The disclosed technology relates to methods, devices, systems and computer program products that facilitate access to metadata associated with a content. In one example, a method is described that includes receiving a multimedia content at a receiver device, extracting a watermark message from a first segment of the multimedia content, using at least a portion of the first watermark message to obtain additional information regarding the first segment of the multimedia content that includes the first watermark message, and associating and storing one or more values of the first watermark message and the additional information. The method further includes repeating the above operations to extract additional watermark messages from additional segments of the content and to form a table or array of items that can be accessed by specifying the one or more values of the first watermark message or one or more values of the additional watermark messages.

System and method for signaling security and database population

The disclosed embodiments relate to media devices implementing new television standards, such as ATSC 3.0, which includes audio/video essence and metadata/signaling. The disclosed embodiments include techniques for creating a signaling file that contains metadata and signaling data about the broadcast service being presented. The signaling file may include URLs that can be used to access signaling information for supplementary signaling and content. The signaling also contains a mapping between a first timing system and a second timing system. The first timing system may comprise the watermark timeline represented in interval s and the second timing system may comprise a DASH presentation time.

Watermark-based metadata acquisition and processing

Methods, devices, systems and computer program products facilitate accessing metadata associated with a primary audio visual content. Upon reception of a primary content, one or more watermark messages are extracted from the primary content obtain a server code and an interval code. A query to a metadata server is initiated based on the information obtained from the extracted watermark messages. In response to the query, service recovery information is received that includes information identifying one or more timed events, where each timed event identifies an operation to be performed at a corresponding instance in time as the primary content is being presented by the receiver device. One or more operations identified the timed events are initiated at the corresponding instance(s) in time.

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San Diego, CA, United States of America

Jian Zhao