Danisco US Inc.

Genencor International, Inc.

Zimmer Gmbh

Nvidia Corporation

The Goodyear & Tire Rubber Company

Zimmer Orthobiologics, Inc.

Genecor International, Inc.

Isto Technologies, Inc.

Danisco US Inc., Genencor Division

Zimmer Orthobiologies, Inc.

Daniaco A/s, Genencor Division

Zimmer Orthobiologicals, Inc.

The Procter Gamble Company

Jian Yao

Frits Goedegebuur

Michael C Ward

Nigel S Dunn-Coleman

David Aaron Estell

Richard Ray Bott

Cheryl Renee Blanchard

Lilia Maria Babe

Robert C Spiro

Neil Kizer

Katherine Augustyn

Sina Pricelius

James T Kellis, Jr

Victor Zaporojan

Michael D Ward

Derek H Wells

Zachary Quinn Beck

Joshua Roy Basler

Miles Christopher Scotcher

Jeffrey W Munos

Roopa Santosh Ghirnikar

James T Kellis

Glenn Steven Ward

Philip Frank Souter

Ayrookaran J Poulose

Katherine D Collier

Luis Gustavo Cascao-Pereira

Neelam S Amin

Gudrun Vogtentanz

Rie Mejldal

Marc Anton Bernhard Kolkman

Chia-Chih Chen

Jizong Gao

Michael Stoner

Adam Garske

David Marquez

Neeraj Pandey

Mansi Rankawat

Priyanka Chandrasekaran

Edward M Concar

Dong Zhang

Christian D Adams

Luis Gustavo Cascão-Pereira

Euan John Magennis

Marc Kolkman

Piet Van Solingen

Anita Van Kimmenade

Harm Jan Mulder

Viktor Alekseyev

Alexander Pisarchik

Xiaogang Gu

Hui Liu

Hali Wang

Hai-Qing Xian

Ben Walthall

Rodney Bristol

Phillip Frank Souter

Essy Behravesh

Xiao Huang

Pieter Van Solingen

Jeffrey Veach Miller

Viktor Yuryevich Alekseyev

James T Kellis Jr

Ayrookaran Joseph Poulose

Jr James T Kellis

Daniel Esteban Torres Pazmino

Shukun Yu

Harm Mulder

The present disclosure provides AprL-clade protease enzymes, including variant AprL-clade protease enzymes, nucleic acids encoding same, and compositions and methods related to the production and use thereof, including an AprL-clade variant subtilisin enzyme that has improved stability and/or soil removal compared to a parent AprL-clade subtilisin enzyme.

AprL-clade protease variants and uses thereof

Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, where the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising the cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding the cellulase variants, or active fragments thereof; and methods for making and/or using the cellulase variants, or active fragments thereof and/or compositions containing same; where the cellulase variants, or active fragments thereof, have endoglucanase activity.

Polypeptides with endoglucanase activity and uses thereof

Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.

Protease variants and uses thereof

In various examples, sensor data may be received that represents a field of view of a sensor of a vehicle located in a physical environment. The sensor data may be applied to a machine learning model that computes both a set of boundary points that correspond to a boundary dividing drivable free-space from non-drivable space in the physical environment and class labels for boundary points of the set of boundary points that correspond to the boundary. Locations within the physical environment may be determined from the set of boundary points represented by the sensor data, and the vehicle may be controlled through the physical environment within the drivable free-space using the locations and the class labels.

Determining drivable free-space for autonomous vehicles

Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more-clade subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.

-clade serine proteases

AprL-clade subtilisin protease variants and uses thereof

The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.

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This present invention relates to cultured recombinant cells comprising heterologous phosphoketolase (PKL) polypeptides that are capable of increased production of acetyl coenzyme A-derived metabolites, as well as methods for producing and using the same. In some embodiments, the recombinant cells further comprise one or more mevalonate (MVA) pathway polypeptides for the production of isoprenoid precursors, isoprene and isoprenoids.

Phosphoketolases for improved production of acetyl coenzyme A-derived metabolites, isoprene, isoprenoid precursors, and isoprenoid

This present invention relates to cultured recombinant cells comprising a heterologous phosphoketolase (PKL) polypeptide that are capable of increased production of acetyl coenzyme A-derived metabolites, as well as methods for producing and using the same. In some embodiments, the recombinant cells further comprise one or more mevalonate (MVA) pathway polypeptides for the production of isoprenoid precursors, isoprene and isoprenoids.

Phosphoketolases for improved production of acetyl coenzyme A-derived metabolites, isoprene, isoprenoid precursors, and isoprenoids

Aspects of the present compositions and methods relate to novel metalloproteases, polynucleotides encoding the novel metalloproteases, and compositions and methods for use thereof.

Metalloproteases

The present invention provides serine protease variants, more specifically subtilisin variants produced there from. Specifically, the present invention provides serine protease variants, more specifically subtilisin variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants, more specifically subtilisin variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants, more specifically subtilisin variants.

Compositions and methods comprising serine protease variants

Growing community of inventors

Sunnyvale, CA, United States of America

Jian Yao