Children's Medical Center Corporation

Other

University of California

Cree Gmbh

Jian Xu

Stuart H Orkin

Daniel E Bauer

Yifeng Wu

Lee Mc Carthy

Naiqing Zhang

Naiqian Zhang

Lee Mccarthy

Provided herein are methods and compositions for increasing fetal hemoglobin levels in a cell by disrupting BCL11A expression at the genomic level. Also provided herein are methods and compositions relating to the treatment of hemoglobinopathies by reinduction of fetal hemoglobin levels.

Targeting BCL11A distal regulatory elements for fetal hemoglobin reinduction

New Group III nitride based field effect transistors and high electron mobility transistors are disclosed that provide enhanced high frequency response characteristics. The preferred transistors are made from GaN/AlGaN and have a dielectric layer on the surface of their conductive channels. The dielectric layer has a high percentage of donor electrons that neutralize traps in the conductive channel such that the traps cannot slow the high frequency response of the transistors. A new method of manufacturing the transistors is also disclosed, with the new method using sputtering to deposit the dielectric layer.

Group III nitride based FETs and HEMTs with reduced trapping and method for producing the same

Growing community of inventors

Plano, TX, United States of America

Jian Xu