Shenzhen Mindray Bio-medical Electronics Co., Ltd.

Honor Device Co., Ltd.

Huawei Technologies Co., Limited

Jian Xie

Chenlong Li

Ruifeng Li

Bo Liu

Gengwen Chen

Ruixia Song

Lipeng Qi

Provided are a method for preparing reticulocyte simulating particles and platelet simulating particles, and a reference control. The method for preparing the reticulocyte simulating particles comprises: staining mammalian anucleated red blood cells having a volume of 60-120 fL with a protein fluorescent dye activated by N-hydroxysuccinimide, and fixing the anucleated red blood cells to prepare the reticulocyte simulating particles. The platelet simulating particles are prepared from mammalian anucleated red blood cells having a volume of 2-25 fL, and the steps of preparing the platelet simulating particles are the same as that for the reticulocyte simulating particles. The preparation method comprises: using an protein fluorescent dye activated by N-hydroxysuccinimide to stain mammalian anucleated red blood cells having different volumes, so as to respectively obtain reticulocyte simulating particles and platelet simulating particles. The fluorescence and volume direction thereof in the scatter diagram are similar to the scatter diagram distribution of reticulocytes, reticulated platelets and platelets in fresh blood. The prepared simulating particles have good stability and do not interfere with the counting and differentiation of other cell particles.

Method for preparing reticulocyte simulating particles and platelet simulating particles, and reference control

Erythrocyte simulating particles, a preparation method therefor, and a quality control or calibrator containing the erythrocyte simulated particles. The method for preparing erythrocyte simulating particles includes: performing oxidization and fixation treatments on erythrocytes by using an erythrocyte treatment solution that has a pH of 5.0-9.0 and an osmotic pressure of 300-800 Osm/kg·HO, wherein the erythrocyte treatment solution contains at least one oxidization agent selected from halogen oxygen acid salts and at least one fixation agent selected from aldehydes or acids; and washing the erythrocytes treated by the erythrocyte treatment solution and suspending the same in a preservation solution. The described method uses an environmentally friendly halogen oxygen acid salt as an oxidant, to obtain erythrocyte simulating particles that can be stored stably for a long time and have properties similar to natural erythrocyte particles in an erythrocyte detection channel.

Erythrocyte simulating particle, preparation method therefor, and quality control or calibrator containing same

This application discloses an infrared light transmit apparatus and a mobile terminal in which the infrared light transmit apparatus is applied. The infrared light transmit apparatus includes an infrared light transmitter and a light cover, where the light cover includes a fixing post and a positioning station that are connected to each other; the fixing post includes a light-in surface and a light-out surface that are disposed opposite to each other and includes a side surface connecting the light-in surface and the light-out surface, the light-in surface is connected to the positioning station, the light-out surface is away from the positioning station, and the side surface is configured to fit a housing of the mobile terminal, so that the light cover is fastened to the housing; and a light concentration surface is formed on a side that is of the positioning station and that is away from the fixing post, the light concentration surface includes a concave curved surface, the light concentration surface faces towards the infrared light transmitter to receive infrared light transmitted by the infrared light transmitter.

Infrared light transmit apparatus and mobile terminal

Growing community of inventors

Shenzhen, China

Jian Xie