Zhejiang Dahua Technology Co., Ltd.

Zhejiang University

State Grid Corporation of China

Acea Biosciences, Inc.

Acea Therapeutics, Inc.

Agilent Technologies, Inc.

Altenergy Power System, Inc.

Taizhou Power Supply Company of State Grid Zhejiang Electric Power

Central South University

Jiaxing Jackson Travel Products Co., Ltd.

Lynk Pharmaceuticals Co. Ltd.

State Grid Shaanxi Electric Power Research Institute

State Grid (xi'an) Environmental Protection Technique Center Co. Ltd

Huawei Technologies Co., Limited

Beijing University of Posts and Telecommunications

Jian Wu

Xiaobo Wang

Jun Yin

Jun Wu

Xingming Zhang

Jiangming Zhu

Liquan Fu

Nan Li

Ye Chen

Long Mao

Jianwei Yin

Shuiguang Deng

Ying Li

Tianxing Wang

Zhaohui Wu

Jia Liu

Min He

Yile Chen

Yuning Hua

Kongen Dai

Zhen Huang

Xiao Xu

Yuhao Luo

Guode Ying

Tao Zhu

Hua Xu

Kang Wang

Yuande Zheng

Hao Tan

Zaibing Zhou

Hao Li

Yongchun Yang

Biaojie Qi

Wei Wang

Jing Li

Xiaodong Li

Zhaokui Wan

Zhen Wang

Xuelin Zhu

Chi Zhang

Xiong Li

Liang Chen

Xin Liu

Bin Liang

Yi Wang

Xin Yao

Yan Zhang

Yue Liu

Zhicheng Ye

Yimei Bao

Bojie Weng

Ping Zhao

Xiaopeng Mo

Yutao Qiu

Yiping Shen

Xiaotong Zhu

Michael Lawrence Vazquez

Chen Zhou

Yujun Gao

Dapeng Zhang

Jintong Lin

Ben Li

Xiaochun Xu

Qingchun Zhao

Zhiling Luo

Wanhong Xu

Jiong Zhu

Jinjuan Huang

Wenqiu Zeng

Honglei Sun

Xu Jiang

Longbin Fang

Qiting Ye

Bingyun Lv

Lingbo Kong

Yongjia Zhou

Rijun Wang

Huajiang Yan

Dongliang Sheng

Chenge Liao

Zhuqiang Bao

Yun Xie

Xi-aopeng Mo

Qiang Sun

Yin Chen

Jingling Lu

Zili He

De Ding

Wanjie Wang

Shao Yang

Genzhou Zhang

Zhenqi Weng

Xiaochun Bai

Zheng Qin

Anxiang Guo

Yantao Zhang

Zhi Tao

Pinghai Lv

Xiaobing Yu

The invention relates to solid forms of certain N-(pyrimidinyloxy)acrylamide derivatives that are useful in the treatment of proliferation and immunological disorders and other diseases related to the dysregulation of kinases including EGFR (including HER), Alk, PDGFR, BLK, BMX/ETK, BTK, FLT3 (D835Y), ITK, JAK1, JAK2, JAK3, TEC and TXK. The invention provides methods of making these materials and their salts and polymorphs, and intermediates for preparing these materials, as well as pharmaceutical compositions comprising these materials. The solid forms and pharmaceutical compositions comprising them are useful to treat conditions including a proliferation disorder, a tumor, an inflammatory disease, an autoimmune disease, psoriasis, dry eye, rheumatoid arthritis, or lupus.

Process for manufacture of (S)-N-(3-((2-((4-((1-acetylpyrrolidin-3-yl)(methyl)amino)phenyl)amino)-5-methoxypyrimidin-4-yl)oxy)phenyl)acrylamide, and formulations thereof

A dense optical flow calculation system and method based on an FPGA (Field Programmable Gate Array) are provided. The system comprises a software system deployed on a host and a dense optical flow calculation module deployed on the FPGA. Pixel information of two continuous frames of pictures is obtained from a host end in the system, and optical flow is obtained by calculation by means of the steps such as smoothing processing, polynomial expansion, intermediate variable calculation, optical flow calculation. An image pyramid and iterative optical flow calculation can be achieved by repeatedly calling a calculation core module in the FPGA; a final calculation result is returned to the host end.

Dense optical flow calculation system and method based on FPGA

Provided in the present disclosure is crystal form I of compound 1, and a preparation method thereof and the use thereof.

Crystal form of pyrazolyl-amino-pyrimidinyl derivative, and preparation method therefor and use thereof

A three-phase grid-connected inverter, a control system thereof and a control method therefor. The inverter is a three-phase three-leg grid-connected inverter, and a filter capacitor is connected to a negative electrode of a DC input bus to form a filter loop, so as to filter harmonic wave in the circuit, realizing high-quality grid-connected current at small power, without increasing an inductance value, so that the parallel inverter device in the system operates stably and thus is applicable to photovoltaic microinverters. Moreover, the three-phase three-leg grid-connected inverter operates in a discontinuous conduction mode, that is, in a switching cycle, the inductive current is reduced to 0, so that the switching loss of the three-phase three-leg grid-connected inverter is reduced.

Control method and system for three-phase grid-connected inverter, and three-phase grid-connected inverter

Disclosed is a confining pressure-adjustable test and observation system for soil deformation features during vacuum preloading. The system includes a soil vacuum consolidation system, a vacuum drive system, a confining pressure system and a monitoring system; where the soil vacuum consolidation system includes a model box filled with test soil, the confining pressure system is arranged in the model box, two sides of the model box are provided with slide plates, and the slide plates on two sides are provided with expansion control cavities at two side ends of the model box correspondingly, and a corrugated air bag is arranged in the expansion control cavity and is connected to an external air pump and an air bag air pressure control device through a pipeline; the test soil in the model box is covered with geotextile, and the geotextile is covered with a vacuum film.

Confining pressure-adjustable test and observation system for soil deformation features during vacuum preloading and test method

Provided is a determination method of differential protection suitable for an electricity transmission line with multi-terminal T-connection. The determination method includes: sampling and calculating all phase currents, and calculating a maximum fault component current &#x394;&#x130;in phase current amplitudes of each phase current, a differential current Iin the each phase current, a resistive current Iin the each phase current and a vector sum &#x394;&#x130;of fault component currents except &#x394;&#x130;in the phase current amplitudes of the each phase current; and comparing the maximum fault component current &#x394;&#x130;in phase current amplitudes of each phase current and a threshold setting value I, determining a value of a resistive coefficient K corresponding to the phase current amplitudes of the each phase current according to a comparison result, and performing differential determination on the differential current Iand the resistive current Iin phase current amplitudes of the each phase current according to a differential determination formula: if the differential current Iof the target phase satisfies the above differential determination formula, it is determined that a fault occurs in an area of the target phase.

Differential protection determination method

A three-phase grid-connected inverter, and a method and a device for controlling the three-phase grid-connected inverter are provided. The method is applied to a three-phase three-leg grid-connected inverter. A structure of the three-phase three-leg grid-connected inverter is improved, so that a filter capacitor (C, C, and C) is connected to a negative electrode of a direct current input bus to form a harmonic bypass circuit. Inverter devices connected in parallel in the system operate stably without increase of inductance of an inductor (L, L, L). In addition, the three-phase three-leg grid-connected inverter according to the present disclosure operates in a discontinuous mode of inductor current (i, i, and i). That is, in the process that a power switch transistor (Q, Q, Q, Q, Qand Q) on bridge legs is turned on, the inductor current (i, i, and i) drops to zero.

A cleaning tool with a spin-drying bucket, comprising a hand-operated rotary mop () and a bucket (), the hand-operated rotary mop () comprises an upper rod () and a lower rod () disposed in a nested arrangement, the upper rod () extends telescopically from the lower rod (), and the lower rod () rotates relative to the upper rod (), a driving mechanism disposed between the upper rod () and the lower rod () converts a telescopic motion of the upper rod () into a rotary motion of the lower rod (), the lower rod () has a mop head () with a wiper disposed at a bottom of the lower rod (); a transmission shaft (), used for connecting to the mop head (), is disposed in the bucket (), a water spray mechanism () having a squeezing component () for spraying water to the wiper, is disposed in the bucket (), when the mop head () is connected to the transmission shaft (), the rotation of the lower rod () drives the transmission shaft (), the mop head (), and the squeezing component () of the water spray mechanism () to rotate together around a same axis and/or at a same speed.

Cleaning tool with a spin-drying bucket

A method and system of graph feature extraction and graph classification based on adjacency matrix is provided. The invention first concentrates the connection information elements in the adjacency matrix into a specific diagonal region of the adjacency matrix which reduces the non-connection information elements in advance. Then the subgraph structure of the graph is further extracted along the diagonal direction using the filter matrix. Further, it uses a stacked convolutional neural network to extract a larger subgraph structure. On one hand, it greatly reduces the amount of computation and complexity, getting rid of the limitations caused by computational complexity and window size. On the other hand, it can capture large subgraph structure through a small window, as well as deep features from the implicit correlation structures at both vertex and edge level, which improves speed and accuracy of graph classification.

System and method of graph feature extraction based on adjacency matrix

The present invention relates to methods of making certain pyrrolopyrimidine derivatives, which are useful in the treatment of proliferation disorders and other diseases related to the dysregulation of kinase (such as, but not limited to, EGFR (including HER), Alk, PDGFR, BLK, BMX/ETK, BTK, FLT3(D835Y), ITK, JAK1, JAK2, JAK3, TEC and TXK) and/or the respective pathways, salts, polymorphs, and amorphous forms of said compounds, synthetic intermediates for preparing said compounds, and pharmaceutical compositions comprising said compounds and methods for making such compositions. 

Pharmaceutical composition comprising N-(3-((2-((3-fluoro-4-(4-methylpiperazin-1-yl phenyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)phenylacrylamide

Disclosed is system and method of connection information regularization, graph feature extraction and graph classification based on adjacency matrix. By concentrating the connection information elements in the adjacency matrix into a specific diagonal region of the adjacency matrix in order to reduce the non-connection information elements in advance. The subgraph structure of the graph is further extracted along the diagonal direction using the filter matrix. Then a stacked convolutional neural network is used to extract a larger subgraph structure. On the one hand, it greatly reduces the amount of computation and complexity, solving the limitations of the computational complexity and the limitations of window size. And on the other hand, it can capture large subgraph structure through a small window, as well as deep features from the implicit correlation structures at both vertex and edge level, which improves the accuracy and speed of the graph classification.

System and method of connection information regularization, graph feature extraction and graph classification based on adjacency matrix

Disclosed is a multifunctional water spray mop, which comprises a mop rod, a water spray mechanism arranged on the mop rod, and a mop head arranged at the tail end of the mop rod. The water spray mechanism comprises a water tank, a pump body in communication with the water tank, and a nozzle in communication with the pump body. The water spray mechanism is detachably arranged on the mop rod. The water spray mechanism is further provided with a connecting component used for connecting other cleaning components, and a press mechanism used for manually operating the pump body to spray a liquid in the pump body out of the nozzle.

Multifunctional water spray mop

A system for detecting signal components of light induced by multiple excitation sources including: a flow channel including at least two spatially separated optical interrogation zones; a non-modulating excitation source that directs a light beam of a first wavelength at a near constant intensity onto a first of the optical interrogation zones; a modulating excitation source that directs a light beam of a second wavelength with an intensity modulated over time at a modulating frequency onto a second of the optical interrogation zones; a detector subsystem comprising a set of detectors configured to detect light emitted from particles flowing through the at least two optical interrogation zones and to convert the detected light into a total electrical signal; and a processor that determines signal components from the light detected from each of the optical interrogation zones.

System and method for detecting multiple-excitation-induced light in a flow channel

Instrument for analyzing biological cells

A self-wringing foam cotton mop includes a mop rod and a foam cotton head connected to a bottom end of the mop rod. A wringing frame is disposed on the mop rod. During mopping, the foam cotton head is separated from the wringing frame. A squeezing mechanism capable is disposed on the wringing frame. The position of the squeezing mechanism when the foam cotton head is moved up relative to the wringing frame is different from the position of the squeezing mechanism when the foam cotton head is moved down relative to the wringing frame, and a first amount of deformation generated by the foam cotton head during an upward movement of the foam cotton head relative to the wringing frame is greater than the second amount of deformation generated by the foam cotton head during a downward movement of the foam cotton head relative to the wringing frame.

Self-wringing foam cotton mop with labor-saving wringing operation

Growing community of inventors

Hangzhou, China

Jian Wu