Allelix Biopharmaceuticals Inc.

Jian-Min Fu

Ashok Tehim

Sumanas Rakhit

Robert A Kirby

Described herein are D4 receptor-selective compounds of the general formula: ##STR1## wherein: A and B are independently selected, optionally substituted, saturated or unsaturated 5- or 6-membered, homo- or heterocyclic rings;

Dopamine receptor ligands

Described herein are D4 receptor-selective compounds of the general formula: ##STR1## wherein X.sub.1 is selected from CH.sub.2, NH, O and S;

N- methyl piperazine compounds having dopamine receptor affinity

Described herein are D4 receptor-selective compounds of the general formula: ##STR1## wherein: A and B are independently selected, optionally substituted, unsaturated 5- or 6-membered, homo- or heterocyclic rings;

Alkyl-substituted compounds having dopamine receptor affinity

Benzyl-substituted compounds having dopamine receptor affinity

N-methyl piperazine compounds having dopamine receptor affinity

Described herein are 5-HT2 receptor-selective compounds of Formula I: ##STR1## wherein: A and B are independently selected, optionally substituted, saturated or unsaturated 5- or 6-membered, homo- or heterocyclic rings;

Growing community of inventors

Brampton, Canada

Jian-Min Fu