Linkchem Co., Ltd., Shanghai

Jiaming Cai

Yong Fang Liang

Xi Lu

Shuai Liu

Yuan Zeng

Quan Tang

The present disclosure discloses a method for synthesizing a diaza-bridged compound and a diaza-bridged compound, belonging to the field of organic synthesis. The present disclosure includes the following reaction:  in the formula, R is aryl, substituted aryl, alkyl or haloalkyl, Ris any one of H, 2-nitrobenzenesulfonyl, 4-nitrobenzenesulfonyl or 2,4-dinitrobenzenesulfonyl, n=1 or 2. Since compound 2 and NHare used as raw materials, the present disclosure can not only effectively shorten the process flow and save process costs, but also improve the reaction yield to a certain extent. The present disclosure also provides a diaza-bridged compound, where the structural formula thereof is  in the formula, Ris any one of 2-nitrobenzenesulfonyl, 4-nitrobenzenesulfonyl or 2,4-dinitrobenzenesulfonyl. Since the compound has a higher melting point, is easy to recrystallize to get solid and not easy to form oil under high temperature, the diaza-bridged compound is suitable for long-distance transportation and long-term storage.

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Shanghai, China

Jiaming Cai