Zhejiang Huahai Pharmaceutical Co., Ltd.

Shanghai Synergy Pharmaceutical Sciences Co., Ltd.

Jiamiao Wang

Lei Liu

Xin Xu

Yunfei Li

Jian Ge

Yijin Wang

Zhiyun Wang

Lihong Lin

Zhen Zhang

Tao Cheng

Dongsheng Li

Liming Zhang

Xiaoer Xia

Xiaojuan Zhang

Dengxue Sun

A powder injection of a donepezil semi palmoxiric acid salt, a composition containing the same and a preparation method therefor. The powder injection contains donepezil semi palmoxiric acid salt crystals having an average particle size of 2-52 &#x3bc;m.

Powder injection of the donepezil semi palmoxiric acid salt, composition containing same and preparation method therefor

A powder injection of a donepezil semi palmoxiric acid salt, a composition containing the same and a preparation method therefor. The powder injection contains donepezil semi palmoxiric acid salt crystals, and the average grain size of the crystals ranges from 0.5 &#x3bc;m to 100 &#x3bc;m.

Provided are a compound of the formula below, and a pharmaceutically acceptable salt or stereoisomer thereof that can be used for treating cardiovascular diseases and compositions containing the compounds. The compounds, a pharmaceutically acceptable salt or stereoisomer thereof and the compositions can improve lipid metabolism disorders by increasing high-density lipoprotein cholesterol in blood; in addition, the compounds, a pharmaceutically acceptable salt or stereoisomer thereof and the compositions can also release nitric oxide, and reduce the onset risk of cardiovascular diseases by means of relaxing blood vessels, lowering blood pressure, inhibiting platelet adhesion and aggregation and maintaining vascular tension, and thus play an important role in preventing and treating the occurrence and development of cardiovascular diseases. 

Nitric oxide-releasing prodrug molecule of substituted quinazolines

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Shanghai, China

Jiamiao Wang