Crystal Pharmaceutical (suzhou) Co., Ltd.

Jiale Qian

Yanfeng Zhang

Minhua Chen

Chaohui Yang

Xiaoting Zhai

Chunxiang Huang

Yuhao Chen

Liping Meng

The present invention provides novel crystalline forms of Xevinapant and preparation methods thereof, pharmaceutical compositions containing the crystalline forms, and uses of the crystalline forms for preparing IAPs drugs and drugs for treating LA SCCHN.

Crystal form of Xevinapant for treating LA SCCHN

The present disclosure relates to novel crystalline forms of ARN-509 (structure shown in formula I), processes for preparation of the novel crystalline forms, pharmaceutical composition of the novel crystalline forms, and uses of the novel crystalline forms for preparing drug products of androgen receptor antagonists and for treating prostate cancer. The crystalline forms of ARN-509 provided by the present disclosure have one or more improved properties compared with the prior art, and is of great value to the future optimization and development of drugs. 

Crystalline forms of ARN-509, preparation method and use thereof

Growing community of inventors

Suzhou, China

Jiale Qian