Jiangsu Chengyang Crop Science Co., Ltd.

Traffic Management Research Institute of the Ministry of Public Security

Jiabin Hu

Xiaojun Wang

Chuanhui Yu

Minghua Xu

Qin Wan

Shangcheng Xu

Dongbo Liu

Jin Huang

Zhengliang Sun

Gang Cai

A method is for preparing 1-(4-chlorophenyl)-2-cyclopropyl-1-propanone and an intermediate thereof, where in the method for preparing a compound of formula (I), &#x3b1;-alkoxy p-chlorobenzyl phosphonate (II) and cyclopropyl methyl ketone are used as raw materials, and subjected to a Homer-Wadsworth-Emmons reaction in an organic solvent in the presence of a base, so as to prepare a derivative of alkoxy propylene with the structure of formula (III); and the resulting derivative of alkoxy propylene (III) is hydrolyzed under acidic conditions to obtain 1-(4-chlorophenyl)-2-cyclopropyl-1-propanone (I).

Method for preparing 1-(4-chlorophenyl)-2-cyclopropyl-1-propanone and intermediate thereof

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Nanjing, China

Jiabin Hu