Y-Biologics Inc.

Ji-Young Shin

Young Woo Park

Bum-chan Park

Seok Ho Yoo

Jae Eun Park

Youngja Song

Sunha Yoon

Yunseon Choi

Sang Pil Lee

Ji Su Lee

Young-Gyu Cho

Jung Chae Lim

Gi Sun Baek

Yeung Chul Kim

Si Hyung Lee

Jisu Lee

Dong Jung Lee

Yeung-Chul Kim

Gisun Baek

A monoclonal antibody or an antigen-binding fragment thereof according to an embodiment of the present invention can bind to lymphocyte-activation gene 3 (LAG-3) including a heavy chain variable region and a light chain variable region and inhibit the activity thereof. Thus it is expected to be useful for the development of immunotherapeutic agents for various disorders that are associated with LAG-3.

Monoclonal antibody specifically binding to LAG-3 and use thereof

The present invention relates to an antibody against delta-like 1 homolog () (DLK1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector comprising the nucleic acid, a cell transformed with the vector, a method for producing the antibody or an antigen-binding fragment thereof, an antibody drug conjugate (ADC) comprising the same, a pharmaceutical composition for treating cancer, a composition for diagnosing cancer, and a chimeric antigen receptor (CAR) and a T-cell engager comprising the same.

Antibody against human DLK1 and use thereof

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Daejeon, South Korea

Ji-Young Shin