Seoul National University

Lg Household & Health Care Ltd.

Lg Chem, Ltd

Bs Research Co. Ltd.

Ji Ung Park

Yan Lee

Suk Wha Kim

Ji Yeon Ham

Hee Jin Kim

Hye Jeong Min

Tae Hyun Choi

Juhan Kim

Wonjae Lee

Minsung Park

Kwang Seoung Jeon

Haesung Yun

Min Ji Kang

Seul Gi Kang

Seung Min Oh

Keum Ok Kim

Jung Hee Won

The present invention relates to a coating composition for an in-vivo implantable prosthesis including a photoinitiator, a crosslinking agent, and a phosphorylcholine (pc) monomer having an acrylate group, a method of coating an in-vivo implantable prosthesis using the coating composition, and a cosmetic prosthesis coated with the crosslinked polyphosphorylcholine. An in-vivo implantable prosthesis coated with crosslinked polyphosphorylcholine may be manufactured by a simple method of applying a coating composition including a photoinitiator, a crosslinking agent, and a phosphorylcholine (pc) monomer having an acrylate group according to the present invention, and then irradiating uv rays. The crosslinked polyphosphorylcholine coating may provide hydrophilicity for the surface and may also remarkably reduce adsorption of proteins and fibroblasts, which may cause side effects such as capsular contracture. Further, the coating has strong enough not to peel off even under stimulation, and therefore, it is maintained under vigorous activity after implantation, thereby being usefully applied to the manufacture of an in-vivo implantable prosthesis with reduced side effects, such as breast prosthesis for cosmetic surgery.

Prosthesis for in vivo insertion, coated with cross-linked polyphosphorylcholine

Provided are a method for manufacturing a mask pack for heavy metal adsorption comprising immersing a cellulose nonwoven fabric in an alkali solution by a cold pad batch method and then aging the cellulose nonwoven fabric at room temperature for 10 minutes to 50 minutes, and immersing the cellulose nonwoven fabric in a carboxymethylation solution by the cold pad batch method and then aging the cellulose nonwoven fabric at room temperature to 60&#xb0; C. for 10 minutes to 3 hours, and a mask pack for heavy metal adsorption manufactured by the method.

Method for manufacturing mask pack for adsorbing heavy metals, and mask pack manufactured thereby

Mask

The present invention relates to a coating composition for an in-vivo implantable prosthesis including a photoinitiator, a crosslinking agent, and a phosphorylcholine (PC) monomer having an acrylate group, a method of coating an in-vivo implantable prosthesis using the coating composition, and a cosmetic prosthesis coated with the crosslinked polyphosphorylcholine. An in-vivo implantable prosthesis coated with crosslinked polyphosphoryicholine may be manufactured by a simple method of applying a coating composition including a photoinitiator, a crosslinking agent, and a phosphorylcholine (PC) monomer having an acrylate group according to the present invention, and then irradiating UV rays. The crosslinked polyphosphorylcholine coating may provide hydrophilicity for the surface and may also remarkably reduce adsorption of proteins and fibroblasts, which may cause side effects such as capsular contracture. Further, the coating has strong enough not to peel off even under stimulation, and therefore, it is maintained under vigorous activity after implantation, thereby being usefully applied to the manufacture of an in-vivo implantable prosthesis with reduced side effects, such as breast prosthesis for cosmetic surgery.

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Seoul, South Korea

Ji Ung Park