Shanghai United Imaging Healthcare Co., Ltd.

Merck Sharp + Dohme Corp.

Intel Corporation

Msd R&d Cn Co., Ltd

Ji Qi

Hao Chen

Na Zhang

Juan Feng

Le Yang

Wanli Teng

Haihua Zhou

Yecheng Han

Kai Cui

Jie Niu

Yange Ma

Hongming Li

Feng Xu

Guy R Humphrey

Richard John Varsolona

Zhiguo Jake Song

Yong-Li Zhong

Artis Klapars

Kevin Campos

Edward Cleator

Kevin Michael Belyk

Jeonghan Park

Tao Wang

Laura Marie Artino

Jingjun Yin

Yonggang Chen

Richard Desmond

Qinghao Chen

Tetsuji Itoh

Louis-Charles Campeau

Xiao-Feng Li

Alan Michael Hyde

Wensong Xiao

Aaron M Dumas

Matthew Thomas Tudge

Rebecca T Ruck

A method and system for image reconstruction are provided. A projection image of a projection object may be obtained. A processed projection image may be generated based on the projection image through one or more pre-process operations. A reconstructed image including an artifact may be reconstructed based on the processed projection image. The artifact may be a detector edge artifact, a projection object edge artifact, and a serrated artifact. The detector edge artifact, the projection object edge artifact, and the serrated artifact may be removed from the reconstructed image.

Image reconstruction system and method

The present invention is directed to a process for making Tetracyclic Heterocycle Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein X, X, R, Rand Rare defined above herein. The present invention is also directed to compounds that may be useful as synthetic intermediates in the process of the invention.

Process for making tetracyclic heterocycle compounds

The present invention includes compounds useful as intermediates in the preparation of macrolactams, methods for preparing the intermediates, and methods for preparing macrolactams. One use of the methods and intermediates described herein is in the production of macrolactam compounds able to inhibit HCV NS3 protease activity. HCV NS3 inhibitory compounds have therapeutic and research applications.

Methods and intermediates for preparing macrolactams

A method comprising calculating first and second allocation speeds respectively for at least a first space and a second space in a runtime environment's memory space; and partitioning the runtime environment's memory space in proportion to said first and second space's respective allocation speeds so that the first space is filled to a first threshold level approximately at the same time as the second space is filled to a second threshold level.

Efficient heap utilization and partitioning

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Shanghai, China

Ji Qi