Abbott Cardiovascular Systems, Inc.

Boston Scientific Scimed, Inc.

Nvision Medical Corporation

Jesus Magana

Kevin Joe Ehrenreich

John Joseph Stankus

Paul M Consigny

David W Snow

Syed F Hossainy

Michael H Ngo

Surbhi Sarna

Benjamyn Serna

Christina Christman-Skieller

Mikael Trollsas

Randolf Von Oepen

Travis Richard Yribarren

Rommel Lumauig

Binh T Nguyen

Lorcan James Coffey

William E Webler, Jr

Gregory Waimong Chan

Alan L Bradley

Sung Woo Min

Shubhayu Basu

Chad Joseph Abunassar

Dariush Davalian

Florian Ludwig

Pamela A Kramer-Brown

Barbara E Stamberg

James Su

William Jason Fox

Albert Chin

David A Mackiewicz

Benny Serna

Albert K Chin

Yuet Mei Khong

Surbhi Sama

Adrain Gale

Evan Norton

Scott Perrin

Sung-Woo Min

According to exemplary embodiments of the present disclosure, a system for collection and analysis of cells from a body lumen of a patient may include a diagnostics device including a tube having a distal end and a proximal end and a balloon having a first end coupled to the distal end of the tube. The balloon may be disposed in the tube in a first, inverted position and movable to a second, everted position. A push wire may have a distal end coupled to a second end of the balloon. The balloon may be movable from the first inverted position to the second everted position by actuation of the push wire. One or more receptacles may be included for processing a balloon sample. The system may further include at least one of a sample preparation fluid, a sample preservation liquid, or both. The sample may be preparable for cytological analysis.

Cell collection and preparation devices and methods

Methods and devices for performing minimally invasive procedures useful for Fallopian tube diagnostics are disclosed. In at least one embodiment, the proximal os of the Fallopian tube is accessed via an intrauterine approach; an introducer catheter is advanced to cannulate and form a fluid tight seal with the proximal os of the Fallopian tube; a second catheter inside the introducer catheter is provided to track the length of the Fallopian tube and out into the abdominal cavity; a balloon at the end of the second catheter is inflated and the second catheter is retracted until the balloon seals the distal os of the Fallopian tube; irrigation is performed substantially over the length of the Fallopian tube; and the irrigation fluid is recovered for cytology or cell analysis.

Methods and devices for fallopian tube diagnostics

The present disclosure generally relates to devices, systems, and methods for Fallopian tube diagnostics. In some embodiments, a tube may have a distal end, and a balloon may be coupled to the distal end of the tube. The balloon may be disposed in the tube in a first, inverted position and movable to a second, everted position. The balloon may be extendable a distance distal of the tube distal end such that a surface of the balloon is contactable with an inner surface of the Fallopian tube. A push wire may have a distal end coupled to a second end of the balloon. The balloon may be movable from the first inverted position to the second everted position by actuation of the push wire. The surface of the balloon may include a plurality of surface features for collection of a tissue sample of the inner surface of the Fallopian tube.

Systems, methods, and devices for fallopian tube diagnostics

The present disclosure generally relates to devices, systems, and methods for Fallopian tube diagnostics. In some embodiments a tube may have a distal end, and a balloon may have a first end coupled to the distal end of the tube. The balloon may be disposed in the tube in a first, inverted position, may be movable to a second, everted position, and may be extendable a distance distal of the tube. An extending portion may have a proximal end coupled to a second end of the balloon. The extending portion may be disposed within the balloon in the first inverted position, and may be extendable from the second end of the balloon in the second everted position.

A method for manufacturing a shaping structure having a generally helical profile and configured to support electrodes for delivering electric energy into a cylindrical lumen of a patient. The method comprises providing a mandrel with a circular cylindrical shape and forming a first hole in the mandrel along the elongate axis, such that opposing ends of a bore of the first hole emerge at the proximal end and at the distal end; forming a second hole in the mandrel to extend from the curved surface to connect with the first hole; wrapping a metal wire around the mandrel; and inserting opposing ends of the metal wire into the second and the third hole respectively, and threading the opposing ends of the metal wire until they emerge from the opposing ends of the bore of the first hole; finally, heating the mandrel and the wire.

System for denervation

Methods and devices for Fallopian tube diagnostics

Method of manufacturing a shaping structure for denervation

A pre-assembled kit for administering ischemic postconditioning comprising a catheter and a handle having a fluid circuit to control and modulate flow of inflation fluid to and from a balloon wherein the catheter is free from additional assembly and preparation procedures such that it is ready-to-use within a variety of vessel sizes.

Catheter system providing step reduction for postconditioning

A catheter apparatus defining a first lumen with a first internal diameter, the catheter apparatus further comprising a shaping structure having a distal end and a proximal end and a length therebetween, the shaping structure being moveable between a delivery state having a first helical shape, and a deployed state having a second helical shape. A deployment member having a second lumen with a second internal diameter, a first portion of the deployment member being positioned within the first lumen and having a third outside diameter sized to enable the deployment member to slide within the first lumen, the deployment member being operably coupled to the distal end of the shaping structure and being configured such that distal axial movement of the deployment member places the shaping structure in the delivery state, and proximal axial movement of the deployment member places the shaping structure in the deployed state.

System and method for a catheter

A polymeric stent can be implanted for treatment of the Eustachian tube. The stent can be designed to have length-dependent radial strength to allow it to stay within the Eustachian tube and to allow normal closing and opening of the Eustachian tube. A balloon can be used to implant the stent, and the balloon can be coated with a therapeutic agent. A coated balloon can also be used to transfer therapeutic agents to the sinus cavity during a balloon sinus dilation procedure.

Devices and methods for treatment of the Eustachian tube and sinus cavity

A catheter apparatus for treatment of a human patient is described, the catheter apparatus having a central axis and comprising a shaping structure moveable between a delivery state having a first helical shape, and a deployed state having a second helical shape. The shaping structure is configured to have a reverse taper with a structural diameter that varies over the length of the shaping structure such that the structural diameter of the shaping structure at the proximal end is smaller than the structural diameter of the shaping structure at the distal end.

System and method for denervation

A catheter capable of rapid inflation and deflation and operation by one individual.

Balloon catheter exhibiting rapid inflation and deflation

A system including a catheter and an expandable member. The catheter includes an independent inflation lumen and an separate independent deflation lumen capable of sequential inflation and deflation of an expandable member in rapid succession, such as less than five seconds.

Catheter having inflation and deflation lumen useful for preventing or reducing reperfusion injury

A system and method for treating a patient including advancing a catheter into the vasculature of the patient, forcing the catheter to adopt a position in contact with a vessel wall, and causing a needle tip to advance into the wall from a lumen in the catheter external surface that is in contact with the wall.

Needle catheter for delivery of agents directly into vessel wall

Apparatus and methods are disclosed for supporting ischemic tissue of the heart using scaffolds that may be placed within the heart percutaneously. A scaffold assembly may include a layer of biocompatible material detachably secured to a placement rod, such that the placement rod may be used to urge the layer of biocompatible material through a catheter to adjacent an area of ischemic tissue. Anchors may secure the layer of material to the myocardium. Multiple layers of biocompatible material may be placed in the ventricle separately to form the scaffold. In some embodiments, a scaffold is formed or reinforced by injecting a polymer, such as a visco-elastic foam, around an inflatable member inflated within a ventricle.

Apparatus and methods for supporting cardiac ischemic tissue

Growing community of inventors

Redwood City, CA, United States of America

Jesus Magana