Allergan, Inc.

St. Jude Medical, Cardiology Division, Inc.

Aga Medical Corporation

Sofregen Medical Ireland Limited

Jessica L Akers

John C Oslund

Matthew Charles Heidner

Enrico Mortarino

Patrick P Russo

Kantilal N Patel

An implantable, pliable silk device (e.g., in a form of a knitted mesh) for use in human soft tissue support and/or repair that provides stretch or pliable properties, e.g., multi-directional elongation properties. Such a device permits physicians or users to alter or manipulate the device dimension and/or shape at the time of device implantation, thereby permitting the device to conform to the contour of a target area or tissue more easily and providing more precise positioning of the device over the target area or tissue. In some embodiments, the implantable pliable silk device comprises a knit pattern feature that substantially prevents unraveling and preserves the stability of the mesh when cut. For example, the pliable silk device is a knitted mesh comprising at least two yarns laid in a knit direction and engaging each other to define a plurality of nodes.

Pliable silk medical device

A vascular device is provided that includes a tubular structure and an occluding structure. The tubular structure has inner and outer layers, with the occluding structure located between the inner and outer layers. Each of the inner and outer layers may define a different pick count, and the tubular structure may include a leading edge at a transition between the pick counts. The leading edge may be disposed at the distal end of the vascular device when the device is deployed from a delivery device. Furthermore, the occluding structure may have first and second layers formed by the inversion or eversion of the occluding structure and the subsequent coupling of its free ends to form a continuous structure. Thus, any loose ends may be sealed to minimize unraveling and/or shifting of the occluding structure within the tubular structure. A method of making the vascular device is also provided.

Device and method for treating vascular abnormalities

An implantable, pliable knitted silk mesh for use in human soft tissue support and repair having a particular knit pattern that substantially prevents unraveling and preserves the stability of the mesh when cut, the knitted mesh including at least two yarns laid in a knit direction and engaging each other to define a plurality of nodes.

Growing community of inventors

Cambridge, MA, United States of America

Jessica L Akers